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Professor Katja Simon awarded Wellcome Trust Investigator Award

Professor Simon has been successful in her Wellcome Trust Investigator Award entitled: “Proteostasis and Autophagy in Immune Senescence.”

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Coronavirus cells © Shutterstock

The NDORMS response to COVID-19

A number of members of the department are actively helping with the response to the COVID pandemic. Playing a key role in research, literature reviews, clinical trials and engineering projects, all have a shared commitment to collaborate globally to tackle the pandemic.

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Syringe containing liquid vaccine © Anna Shvets from Pexels

Drug may boost vaccine responses in older adults

A preliminary study shows that a drug which helps immune cells self-clean may improve vaccine protection in older adults

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Building work on the Kennedy roof

Reach for the sky

A building project to extend the Kennedy Institute of Rheumatology building with a new floor will create much needed space for the Institute to expand, particularly in the areas of data science and clinical trials.

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High-resolution 3D image, tile scan (l) and medulla region (r) of an adrenal gland showing blood vessels (red) and perivascular cells (green and blue)

3D imaging reveals the role of blood vessels in hormone production

New research from the Kusumbe Group at the Kennedy Institute has shown a direct correlation between age-related decline in capillary and artery numbers and hormone production in the endocrine system.

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Kennedy Institute of Rheumatology

A world-leading medical research centre where discovery research drives the development of transformative therapies for chronic inflammatory and degenerative disease.  

240 Staff, students and academic visitors

30 Nationalities

£80M+ in Research Income

Select Publications

Autophagy in T cells from aged donors is maintained by spermidine, and correlates with function and vaccine responses

Alsaleh G. et al, (2020)

Decreased blood vessel density and endothelial cell subset dynamics during ageing of the endocrine system.

Chen J. et al, (2021), EMBO J, 40

A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals.

Demetriou P. et al, (2020), Nat Immunol, 21, 1232 - 1243

The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer.

McCuaig S. et al, (2020), Clin Cancer Res

All publications

Latest news

An experiment being carried out

Oxford to collaborate with Janssen to map the cellular landscape of immune mediated disorders

22 February 2021

Kristina Zec

Versus Arthritis Foundation Fellowship awarded to Dr Kristina Zec

22 February 2021

A montage of images showing 3D scans of mouse spleens and kidneys

Vascular loss shown to be the primary hallmark of aging

4 February 2021

Pile of papers on a table

Immunology preprint reviews launched in Nature Reviews Immunology

15 January 2021

Syringe containing liquid vaccine

Drug may boost vaccine responses in older adults

18 December 2020

More news

COVID-19 research

Coronavirus calls

COVID-19 research at the Kennedy Institute

Find out more about Covid research

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