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Our discovery research examines the key biological processes that maintain tissue health and how these pathways breakdown in disease. We take a multidisciplinary approach, incorporating molecular and cellular biology with analysis of disease models, patient tissue samples and longitudinal clinical data. Our goal is to understand the molecular basis of disease to help develop new therapies or identify biomarkers that can be applied to better manage treatment of disease. We collaborate with clinical centres and industry partners to turn our basic discoveries into new therapies for patients.