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Coronavirus information - what we are doing at NDORMS to support our staff and students and the community

Department

NDORMS announces the closure of the Kennedy and Botnar Institutes and outlines other plans and activities for the department during the pandemic.

Researchers identify markers in joint fluid that could be the key to cartilage repair

General Research

Molecular changes in the joint fluid during surgical joint distraction reveal markers that may drive cartilage repair in osteoarthritis.

CRUK success for NDORMS researchers

Funding

Investigators based at the Kennedy Institute of Rheumatology, NDORMS have recently received CRUK awards to increase understanding of a variety of cancers and immunotherapy.

Two new Associate Professors at NDORMS

Dr Fiona Watt and Professor Stephanie Dakin announced as Associate Professors

New collaboration will help researchers understand why cancer survival between patients differs

NDORMS researchers join five other universities to investigate how cancer survivors make antibodies that target and destroy tumours, and explore routes for new treatments

New therapeutic target identified in spondyloarthritis

A new study published in Nature Communications identifies a key driver of joint and intestinal inflammation that could lead to future treatment of the chronic inflammatory disease.

Cancer progression may be controlled by targeting tumor-specific extracellular matrix

Research

Researchers have uncovered how tumors exploit tenascin-C to deflect the body’s natural defence against them.

Researchers identify link in the treatment of inflammatory bowel disease (IBD)

Research

A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance

NDORMS team awarded the International Dupuytren Award

Awards

Jagdeep Nanchahal, Professor of Hand, Plastic and Reconstructive Surgery at the Kennedy Institute, and his team have won the International Dupuytren Award for a trial repurposing anti-TNF in Dupuytren’s disease.

Dissecting TNF signalling in inflammatory disease

Research

New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.

NDORMS careers event: transitioning from postdoc to PI

A careers event held by NDORMS offered information and advice to postdoctoral researchers transitioning to becoming independent group leaders.

Synthetic cells capture and reveal hidden messages of the immune system

When immune cells detect harmful pathogens or cancer, they mobilise and coordinate a competent defence response. To do this effectively immune cells must communicate in a way that is tailored to the pathogenic insult. Consequently, the body's response to various health challenges depends on successful coordination among the cells of the immune system.

Naturally occurring compound spermidine boosts vaccine responses in old mice

Researchers at the Kennedy Institute identify a molecular pathway to boost vaccine responses in the elderly.

Kennedy researchers join UK inflammatory arthritis research centre

Oxford is the newest partner of the national Research into Inflammatory Arthritis Centre Versus Arthritis (RACE) which has been awarded continued funding of nearly £2m over the next five years from Versus Arthritis.

Study links blood vessels to therapy resistance in cancer metastasis to bone

Research

A new study from the Kennedy Institute of Rheumatology reveals a role for blood vessels in promoting therapy resistance of cancer metastasis in bone.

Bringing patients closer to arthritis research

The Kennedy Institute recently hosted a visit from the National Rheumatoid Arthritis Society (NRAS) to explore opportunities to partner on patient involvement approaches in arthritis research.

Kennedy Trust renews commitment to rheumatology research with £20M

Funding

The Kennedy Trust for Rheumatology Research (KTRR) has pledged a minimum of £20M over five years to the Kennedy Institute of Rheumatology at the University of Oxford to support pioneering research into chronic inflammatory disease.

Kennedy researchers awarded MRC funding for arthritis research

Funding

Congratulations to Kennedy researchers Professor Chris Buckley, Professor Mark Coles and Dr Stephen Sansom who have been awarded £1.5M funding from the Medical Research Council (MRC) to explore fibroblasts as an emerging target to treat chronic inflammatory disease.

Key link discovered between tissue cell type and different forms of arthritis

Pioneering research by scientists at the Universities of Oxford and Birmingham published today in Nature brings us a step closer to developing targeted therapies for inflammatory diseases.

Study reveals new drug target for rheumatoid arthritis

New research at the Kennedy Institute reveals potential of a novel class of drugs for the treatment of rheumatoid arthritis.

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