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New breakthrough in the treatment of rheumatoid arthritis

People with Rheumatoid Arthritis (RA) could soon benefit from a new drug treatment that not only suppresses inflammation but also significantly reduces patient reported pain scores. Otilimab is a monoclonal antibody, biologic drug, which targets and suppresses the inflammatory cytokine GM-CSF.

Wellcome funding awarded to Oxford team to support research into heart muscle regeneration

Awards Research

An Oxford team from the Centre for Medicines Development, Department of Physiology Anatomy and Genetics and Radcliffe Department of Medicine led by Professor Jagdeep Nanchahal at the Kennedy Institute has been awarded a Wellcome Innovator Award to develop a first in class therapeutic aimed at regenerating heart muscle after heart attack.

NDORMS researchers make Highly Cited Researchers list

Awards

Professor Gary Collins, Professor Cyrus Cooper, Professor Fiona Powrie and the late Professor Doug Altman have been named on the annual Highly Cited Researchers™️ 2020 list from Clarivate.

Professor Katja Simon awarded Wellcome Trust Investigator Award

Awards

Professor Simon has been successful in her Wellcome Trust Investigator Award entitled: “Proteostasis and Autophagy in Immune Senescence.”

NDORMS staff recognised for excellence in teaching and research

Awards

Three NDORMS researchers have been awarded new titles in the University of Oxford's 2020 Recognition of Distinction exercise.

European Centre of Excellence at NDORMS

Awards

NDORMS has been designated a EULAR Centre of Excellence 2020-2025, in recognition of our continued high-quality research publications in rheumatology.

An unexpected repair function for neutrophils

Research

In a collaboration with scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), Kennedy researchers have contributed to the discovery that neutrophils have many more functions in the body than previously thought. This finding suggests that neutrophil tissue-specific plasticity could be exploited in designing new treatments for neutrophil driven diseases, including cancer.

Understanding the physics of the immune response necessitates new technology

Research

Professor Marco Fritzsche has joined the Kennedy Institute as the Principal Investigator of the Biophysical Immunology Laboratory (BPI), as part of a joint appointment with the Rosalind Franklin Institute. His lab is leading the development of a lattice light sheet microscope that will significantly advance the study of live cells.

CD2 corolla calls T cells to arms

Research

A team from the University of Oxford has visualised how key cells of the immune system lock onto cancerous or infected cells to destroy them. The work was led by the Mike Dustin’s group at the Kennedy Institute of Rheumatology and experts in colorectal and ovarian cancers from across Oxford and computational biologists at the University of Birmingham.

Likely culprits causing blood vessel lesions in vasculitis identified

NDORMS researchers identify a subset of immune cells that could be a new therapeutic target to treat inflamed blood vessels in Giant Cell Arteritis (GCA) and other forms of inflammatory vascular disease.

Kennedy researcher receives MRC Clinical Training Fellowship

General

Dr Rahul Ravindran has been awarded a highly competitive MRC Clinical Research Training Fellowship, following a successful research placement at the Kennedy Institute in 2019.

Research review reveals potential to improve colon cancer treatments

Researchers at the Kennedy Institute review the growing body of literature on the role of the microbiome in colorectal cancer

Congratulations to our new Associate Professors

The University of Oxford has awarded the title of Associate Professor to Kennedy researchers Tal Arnon and Marco Fritzsche.

Marie Curie Fellowship awarded to Mariana Borsa

Congratulations to Mariana Borsa for being awarded the Marie Skłodowska-Curie Actions – Individual Fellowship

Reach for the sky

General

A building project to extend the Kennedy Institute of Rheumatology building with a new floor will create much needed space for the Institute to expand, particularly in the areas of data science and clinical trials.

Kennedy Professor leads Cellular Life Theme of Reuben College

Professor Mark Coles was recently appointed to the governing body of the University’s newest graduate college.

Joint cell discovery offers new hope for people with rheumatoid arthritis

The key to swift treatments to cure the pain of rheumatoid arthritis has been found in the joints of people with the condition who are in long- term remission.

Sir Marc Feldmann awarded the 2020 Tang Prize in Biopharmaceutical Science

Awards

Recognised for the part he played in the discovery of anti-TNF therapy, Dr Feldmann is now exploring whether the antibody can be effective for COVID-19.

NDORMS professor awarded prestigious Carol Nachman prize for Rheumatology

Awards

Christopher Buckley, Kennedy Professor of Translational Rheumatology at the University of Oxford and Birmingham, has been awarded the 2020 Carol Nachman prize for Rheumatology.

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