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Neutrophil molecular wiring revealed: transcriptional blueprint of short-lived cells

Research

Researchers publish the first blueprint of transcriptional factors that control neutrophil-driven inflammation in Nature Immunology.

Researchers show the role of cilia in cartilage health

New research shows that disrupting primary cilia in juvenile, adolescent and early adulthood in cartilage stops it maturing correctly, making it more prone to thinning and the potential for osteoarthritis (OA) in later life.

Exploring the link between joint injury and osteoarthritis

Research oacentre

A new study published in The Lancet Rheumatology shows potential ways to predict how likely someone is to develop osteoarthritis after a knee injury.

Doctor Ghada Alsaleh awarded a Versus Arthritis Career Development Fellowship

Awards

Postdoctoral Researcher Ghada Alsaleh has been awarded a research grant by Versus Arthritis which she will use to develop a new therapy for osteoarthritis.

New research identifies a role for CD200 in limiting atherosclerosis

A new study published in Circulation Research by researchers at the Kennedy Institute shows that CD200, an inhibitory immune checkpoint, reduces the development of atherosclerosis.

EPSRC funds research to avert an antibiotics apocalypse

Department Funding

Researchers at the Kennedy Institute join a collaboration to find new ‘drug-free’ ways of treating illnesses where current treatments have become ineffective due to antibiotic resistance.

Repurposed drug can induce remission of inflammatory arthritis

Research

Researchers at the Kennedy Institute demonstrate that the drug decitabine can boost regulatory T cell responses.

NDORMS researchers awarded ECTS prizes

Awards

Professor Anjali Kusumbe and Professor Cyrus Cooper have been presented with research awards by the European Calcified Tissue Society (ECTS).

Professor Katja Simon elected to the Academy of Medical Sciences

Awards

Professor of Immunology Katja Simon has been elected as a Fellow of the Academy of Medical Sciences.

Major ERC funding awarded to Professor Michael Dustin

Funding General

Professor Michael Dustin and an international team of collaborators have been awarded a €10M grant from the European Research Council (ERC) to develop a new biotechnology around supramolecular attack particles (SMAPs) engineered to kill cancer cells.

Professor Michael Dustin elected to the National Academy of Sciences

Awards

Recognised for his outstanding contributions to the field of immunology, Michael becomes the fourth Kennedy professor to be elected to the Academy.

Small mechanical forces in immune cells measured at unprecedented sensitivity

Research

Oxford researchers have used advanced microscopy techniques to measure previously unseen forces generated by cells during an immune response; a breakthrough for mechanobiology and future advances in health and disease.

NDORMS researchers awarded for Dupuytren research

Awards

Three NDORMS researchers have received awards from the International Dupuytren Society, a patient organisation that brings together Dupuytren Disease patient societies from across the world.

A new study maps the expression of innate immune receptors during the course of arthritis

The research, which was a collaboration with researchers from Oxford University and Queen Mary University of London and published in Journal of Autoimmunity, looked at changes in receptors known as toll-like receptors (TLRs) in arthritis at different stages of disease.

International Women's Day

It’s International Womens Day! This year’s theme is #Choosetochallenge. We’re celebrating some of the amazing women at NDORMS, and asking them what changes they’d like to see in medical sciences over the next 100 years.

Oxford to collaborate with Janssen to map the cellular landscape of immune mediated disorders

Research

The University of Oxford has entered into a strategic collaboration with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.

Versus Arthritis Foundation Fellowship awarded to Dr Kristina Zec

Awards

Dr Kristina Zec has been awarded a Versus Arthritis Foundation Fellowship to investigate the role of products of lipid oxidation produced by synovial macrophages in triggering articular inflammation.

Vascular loss shown to be the primary hallmark of aging

Research

New Research from the Kusumbe group at the Kennedy Institute of Rheumatology identifies vascular attrition, marked by pericyte to fibroblast differentiation, as a primary hallmark of aging and highlights organ-specific vascular changes with age.

Immunology preprint reviews launched in Nature Reviews Immunology

Research

The Oxford-Mount Sinai (OxMS) Preprint Journal Club has partnered with Nature Reviews Immunology to launch a monthly Preprint Watch column.

Drug may boost vaccine responses in older adults

General Research

A preliminary study shows that a drug which helps immune cells self-clean may improve vaccine protection in older adults

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