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Mitochondrial protein synthesis identified as a potential therapeutic target in lymphoma

Publication Research

A team led by Alex Clarke at the Kennedy Institute has identified how high mitochondrial activity regulates antibody responses crucial for immunity but is also necessary for the development of lymphoma.

Shifting the dogma about synovial lining macrophages: the early drivers of rheumatoid arthritis

Publication Research

Insights into a specific macrophage population suggest that these cells could drive inflammation in rheumatoid arthritis. Understanding their complex role could lead to better treatments for patients.

New partnership will accelerate AI-driven immunotherapies

General

Absci will apply its generative AI platform to The Kennedy Institute’s immunology biorepository to speed the discovery and development of multiple therapies

Professor Michael Dustin elected to the Royal Society

Awards

The Kennedy professor is one of eight researchers from Oxford University who received a prestigious fellowship from the Royal Society in recognition of their work in the fields of science and medicine.

New hope for patients after vedolizumab found effective to treat Chronic Pouchitis

Research

A new study led by Oxford researchers has found vedolizumab can induce remission in patients who have chronic pouchitis after surgery for ulcerative colitis.

New approach to nail bed injury surgery could significantly cut NHS costs

Department Research

According to a new Oxford study, changing clinical practice for finger injuries in children could save the NHS £720,000 per year.

Fat tissues can play a protective role against inflammation in the intestine

Research

A new study in The EMBO Journal has revealed how fat tissues might provide a protective role in intestinal inflammation opening new lines of research into the treatment of inflammatory bowel diseases.

Kennedy researchers awarded Sir Henry Wellcome Fellowships

Funding

Kennedy Institute researchers Mariana Borsa and Edward Jenkins have both been awarded Sir Henry Wellcome Postdoctoral Fellowships, which give recently qualified postdoctoral researchers the opportunity to start independent research careers.

Communication at the crossroads of the immune system

Research

In his inaugural article in the Proceedings of the National Academy of Sciences as an NAS member (elected 2021), Prof Mike Dustin and his research team have explained how messages are passed across the immunological synapse. The research could have implications for future vaccine development and immunotherapy treatments.

The Kennedy Institute launches its single cell facility

Department

We spoke to Irina Udalova and Stephen Sansom about the Kennedy’s new single cell facility and how it will enhance research at the Institute and beyond.

New drug offers hope for people with hand osteoarthritis

Research oacentre

A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models.

Professor Michael Dustin appointed new Chair in Molecular Immunology

Awards Department

A generous gift from the Kennedy Trust for Rheumatology Research has enabled the creation of a new Chair in Molecular Immunology at the University of Oxford.

Two prestigious Hunterian Professorships awarded to NDORMS researchers

Awards General

Conrad Harrison and Tom Layton have both been awarded Hunterian Professorships for 2022 by the Royal College of Surgeons of England

Dr Alex Clarke wins Emerging Leaders Prize for lupus research

Awards

Alex is one of three exceptional lupus researchers that have been announced as winners of the Medical Research Foundation’s sixth Emerging Leaders Prize.

The Kennedy’s research strongly endorsed following independent review

Department

We recently welcomed our Scientific Advisory Board (SAB) and the Kennedy Trust Scientific Review Board (TSRB) to the Institute to review our current activities and future plans.

A new research computing platform advances the understanding of key biological processes in disease

General

To respond to advances in technology and try to answer an increasing range of biological questions, the Kennedy Institute has invested in a high-performance computing facility. We speak to Brian Marsden, Associate Professor of Research Informatics at the Kennedy to find out more.

Adalimumab is found to be a cost-effective treatment for early-stage Dupuytren’s disease

Department Research

Researchers at the Kennedy Institute of Rheumatology and Oxford Population Health’s Health Economics Research Centre have found that anti-TNF treatment (adalimumab) is likely to be a cost-effective treatment for people affected by early-stage Dupuytren’s disease.

Mathematician boosts data science research at the Kennedy Institute

Department

Welcome to Yang Luo who has joined the Kennedy Institute as the Principal Investigator of the Luo Group. Her lab is leading the investigation into how genetic variations contribute to diseases of the immune system.

NIHR funding for musculoskeletal and inflammatory disease research

Department Funding

Health and care research in Oxford is to receive £122 million in government funding over the next five years to improve diagnosis, treatment and care for NHS patients.

Leducq Foundation grant boosts cardiovascular research

Department Funding

The Leducq Foundation has awarded $7.5 million to researchers at the University of Oxford and their collaborators to advance immunotherapy as a treatment for cardiovascular disease, the leading cause of death in the UK.

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