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Connects-UK launches to foster scientific collaborations between EU and UK researchers in a post-Brexit era

General Research

Connects-UK, a new pan-European network dedicated to advancing scientific collaborations between researchers in the European Union (EU) and the United Kingdom (UK), was officially launched at an event in London yesterday. The network, led by a diaspora of EU researchers working in the UK, seeks to bridge the gap created by Brexit and ensure that collaboration, innovative research, funding, and knowledge exchange continue to thrive in the post-Brexit era.

New study reveals how T cells gain and maintain tolerance to gut bacteria


The immune system in the intestine maintains a careful balance, tolerating our long-term resident (commensal) gut bacteria while defending against invading pathogens. Under certain circumstances, dysregulation of our intestinal immune response to commensal and pathogenic microbes can drive inflammatory disease.

PD-1 gets an “A” for team-work


A new understanding of the PD-1 axis (programmed death cell) could help shape ongoing efforts to improve treatments for cancer and autoimmune diseases.

Professor Irina Udalova appointed to the MRC’s Infections and Immunity Board


The Medical Research Council’s Infections and Immunity Board (IIB) funds research into infectious human disease and disorders of the human immune system.

Oxford-ZEISS Centre of Excellence officially opened

Department General Research

ZEISS is partnering with the University of Oxford bringing ground-breaking microscopy imaging equipment, and analysis tools, to advance the study of global health and disease.

CRUK funding success for Audrey Gérard

Funding Research

Audrey Gérard has received £ 1.5 million in funding from CRUK for a new research project to unravel the coevolving cancer and immune landscape.

BBSRC funding awarded to Kennedy researchers to understand how neutrophils develop


A project led by Irina Udalova and co-led by Marco Fritzsche and Erinke van Grinsven, a senior postdoctoral fellow in the Udalova laboratory, has received funding from the Biotechnology and Biological Sciences Research Council (BBSRC) to uncover why and how neutrophils experience dramatic nuclear changes during their development, and the link between maladaptive neutrophil development and chronic inflammation.

Caroline Morrell awarded an MRC Fellowship


A DPhil candidate at NDORMS, Caroline received the MRC Clinical Research Training Fellowship that has enabled her to further her research into head and neck cancer.

Kennedy Trust gift to help drive forward research into inflammatory and musculoskeletal diseases at Oxford

General Research

Two professorships in translational medicine have been endowed at the Kennedy Institute of Rheumatology thanks to a generous gift from the Kennedy Trust for Rheumatology Research.

Tom Hosack awarded an MRC Fellowship


A DPhil candidate at NDORMS, Tom Hosack received the MRC Clinical Research Training Fellowship to further his research into tissue tropism in PD-1 therapy in immune-mediated inflammatory diseases.

New PI will study the mechanical forces impacting cell fate decision-making and tissue dynamics in inflammatory diseases

Department General Research

We welcome Adrien Hallou who has joined the Kennedy Institute as a new Principal Investigator. Adrien will be establishing his lab to better understand the role of mechanical forces on cell fate decisions and tissue dynamics in inflammatory diseases, with a particular focus on inflammatory skin diseases such as psoriasis or atopic dermatitis.

New discovery furthers our understanding of how critical immune cells are controlled during an infection


A recent publication from Audrey Gérard’s lab looks at how a specific protein, called IFNγ, can coordinate CD8+ T cell responses during a flu infection.

University of Oxford DPhil Student attends Kenya Reception at Buckingham Palace


Ruth Nanjala, DPhil student in Molecular and Cellular Medicine funded by the Africa Oxford Initiative (AfOx) Kennedy Trust Prize Studentship, attended a reception at Buckingham Palace hosted by King Charles III and Queen Camilla to mark the 60th anniversary of Kenya’s independence. Ruth was invited in her capacity as student leader within the Oxford University Africa Society (AfriSoc).

Kennedy Trust for Rheumatology Research visits the Kennedy Institute


The Kennedy Trust for Rheumatology Research (KTRR) visited the Kennedy Institute in early October. The Institute benefits extensively from the generous support of the KTRR and the visit was a great opportunity to share stories of our scientific successes and discuss future directions.

New Principal Investigator will study the role of peripheral nerve-associated glial cells in health and disease


We welcome Fränze Progatzky who joined us this month as a new Principal Investigator, establishing her research group to study how glial cells in the nervous system of the gut and the lungs maintain healthy organs and drive responses to infection and injury.

New professor named at the Kennedy


Marco Fritzsche has been honoured in the 2023 Recognition of Distinction Scheme, the University of Oxford’s annual exercise to confer the title of full professor for excellence in research and teaching.

New research endoscopy service launches today


The launch of a new endoscopy service at the Oxford Experimental Medicine Clinical Research Facility (EMCRF) will enhance the collection of data for research projects at NDORMS and across the University of Oxford.

Bioinformatician joins the Kennedy Institute to investigate shared patterns of inflammatory conditions


We welcome Calliope (Calli) Dendrou who joined the Kennedy Institute of Rheumatology this Summer as a Principal Investigator leading a research group. Calli is a leader in cross-disease multiomics and her research focuses on using omics (the study of totality of a molecular process in organisms) to find patterns shared by different inflammatory diseases, so that we can develop better treatments for these life-impacting conditions and repurpose existing treatments to help more people.

The Kennedy Institute celebrates support staff contributions


The lunch with sandwiches, tea and strawberries was attended by staff and students and provided an opportunity to give some well-earned Long Service Awards.

No link found between patient genetics and response to anti-IL17 therapy

Publication Research

A new study looked at the effect of patient genetics on their response to secukinumab, an anti-IL17 therapy commonly used to treat inflammatory conditions including arthritis and psoriasis. No link was found between a patient’s genetic variants and their response to therapy. This study challenges the idea that genetics might significantly account for the variable responses to anti-IL17 therapy seen in the clinic.

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