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Synthetic cells capture and reveal hidden messages of the immune system

Synthetic cells capture and reveal hidden messages of the immune system

When immune cells detect harmful pathogens or cancer, they mobilise and coordinate a competent defence response. To do this effectively immune cells must communicate in a way that is tailored to the pathogenic insult. Consequently, the body's response to various health challenges depends on successful coordination among the cells of the immune system.

Naturally occurring compound spermidine boosts vaccine responses in old mice

Naturally occurring compound spermidine boosts vaccine responses in old mice

Researchers at the Kennedy Institute identify a molecular pathway to boost vaccine responses in the elderly.

Kennedy researchers join uk inflammatory arthritis research centre

Kennedy researchers join UK inflammatory arthritis research centre

Oxford is the newest partner of the national Research into Inflammatory Arthritis Centre Versus Arthritis (RACE) which has been awarded continued funding of nearly £2m over the next five years from Versus Arthritis.

Study links blood vessels to therapy resistance in cancer metastasis to bone

Study links blood vessels to therapy resistance in cancer metastasis to bone

Research

A new study from the Kennedy Institute of Rheumatology reveals a role for blood vessels in promoting therapy resistance of cancer metastasis in bone.

Bringing patients closer to arthritis research

Bringing patients closer to arthritis research

The Kennedy Institute recently hosted a visit from the National Rheumatoid Arthritis Society (NRAS) to explore opportunities to partner on patient involvement approaches in arthritis research.

Kennedy trust renews commitment to rheumatology research with ps20m

Kennedy Trust renews commitment to rheumatology research with £20M

Funding

The Kennedy Trust for Rheumatology Research (KTRR) has pledged a minimum of £20M over five years to the Kennedy Institute of Rheumatology at the University of Oxford to support pioneering research into chronic inflammatory disease.

Kennedy researchers awarded mrc funding for arthritis research

Kennedy researchers awarded MRC funding for arthritis research

Funding

Congratulations to Kennedy researchers Professor Chris Buckley, Professor Mark Coles and Dr Stephen Sansom who have been awarded £1.5M funding from the Medical Research Council (MRC) to explore fibroblasts as an emerging target to treat chronic inflammatory disease.

Key link discovered between tissue cell type and different forms of arthritis

Key link discovered between tissue cell type and different forms of arthritis

Pioneering research by scientists at the Universities of Oxford and Birmingham published today in Nature brings us a step closer to developing targeted therapies for inflammatory diseases.

Study reveals new drug target for rheumatoid arthritis

Study reveals new drug target for rheumatoid arthritis

New research at the Kennedy Institute reveals potential of a novel class of drugs for the treatment of rheumatoid arthritis.

Ukri future leaders fellowship to dr fiona watt

UKRI Future Leaders Fellowship to Dr Fiona Watt

Awards

Dr Fiona Watt has been awarded a prestigious UK Research and Innovation (UKRI) Future Leaders Fellowship to further her research for better treatments for people living with, or at risk of the commonest form of arthritis, osteoarthritis.

Progress in targeting inflammatory disease in the gut and skin

Progress in targeting inflammatory disease in the gut and skin

Two articles from the Kennedy Institute review the latest in understanding immune control in the gut and skin and explain how this knowledge is being translated into new treatments for inflammatory disease

2019 ndorms imaging symposium and awards

2019 NDORMS Imaging Symposium and Awards

Oxford researchers gathered at the Kennedy Institute earlier this month to learn how advanced imaging technologies, such as super resolution microscopy, are pushing the boundaries of scientific discovery.

Showcasing a new approach to arthritis research

Showcasing a new approach to arthritis research

A recent workshop at Pembroke College, Oxford, provided a showcase for research within the Arthritis Therapy Acceleration Programme (A-TAP) aimed at speeding up the delivery of new drugs for immune-mediated inflammatory disease (IMIDs).

Vaccine developed to treat osteoarthritic pain

Vaccine developed to treat osteoarthritic pain

Publication Research oacentre

Researchers have developed a vaccine that blocks the effects of the main cause of pain in osteoarthritis (OA) - nerve growth factor (NGF) - in mice.

Kennedy institute launches oxford centre for microbiome studies

Kennedy Institute launches Oxford Centre for Microbiome Studies

The Oxford Centre for Microbiome Studies (OCMS) provides unique access to essential technologies to speed up our understanding of how the microbes that inhabit our bodies influence health and disease.

New drug class could offer a targeted safer treatment alternative for patients with rheumatoid arthritis

New drug class could offer a targeted safer treatment alternative for patients with rheumatoid arthritis

Publication Research

A new treatment targeting tenascin-C could reduce the progression and severity of rheumatoid arthritis (RA) at the very early stages of disease.

Study suggests immune system plays key role in survival after pancreatic cancer surgery study suggests immune system plays key role in survival after pancreatic cancer surgery

Study suggests immune system plays key role in survival after pancreatic cancer surgery

Publication Research

Researchers in Oxford have found that an individual’s immune system – and in particular the presence of T-cells amongst tumour cells – may play an important role in survival after surgery to remove pancreatic cancer.

Dietary fibre metabolite helps immune system fight invasive bacteria

Dietary fibre metabolite helps immune system fight invasive bacteria

Macrophages treated with the short-chain fatty acid butyrate – a by-product of dietary fibre breakdown - are better equipped to fight bacteria in the gut, report researchers from the Kennedy Institute and the Translational Gastroenterology Unit. These findings could lead to new strategies to restore gut health in inflammatory bowel disease (IBD).

Professor fiona powrie set to talk on cancer grand challenge

Professor Fiona Powrie set to take on cancer 'Grand Challenge'

Oxford scientists are set to benefit from one of the biggest funding grants ever awarded by Cancer Research UK.

Creating a cellular atlas of healthy human joints

Creating a cellular atlas of healthy human joints

Funding

Kennedy researchers, in collaboration with colleagues at the Botnar Research Centre, Oxford, and the Universities of Birmingham and Leeds, have been awarded strategic funding from the Medical Research Council (MRC) to map in detail the different types of cells that make up human joints.

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