22 October 2021
Millions of patients with ulcerative colitis or Crohn’s disease, collectively known as inflammatory bowel disease (IBD), are given fresh hope as a new study shows why some of them do not respond to current treatments.
New drug class could offer a targeted safer treatment alternative for patients with rheumatoid arthritis
15 February 2019
A new treatment targeting tenascin-C could reduce the progression and severity of rheumatoid arthritis (RA) at the very early stages of disease.
12 February 2019
Researchers in Oxford have found that an individual’s immune system – and in particular the presence of T-cells amongst tumour cells – may play an important role in survival after surgery to remove pancreatic cancer.
6 July 2018
Scientists in the Kennedy Institute, NDORMS show anti-TNF inhibits the cells responsible for Dupuytren’s disease.
1 June 2018
Researchers at the Kennedy Institute and the University of York develop a new imaging approach that offers superior resolution to track the movement of soluble proteins in tissues.
9 January 2018
New research published in Cell Reports by the Dustin Group has discovered a new way for immune cells to relay information about infection or genetic mutations through dynamic, yet durable cell contacts before deciding how to respond.
20 December 2017
A recent publication from the Powrie group at the Kennedy Institute of Rheumatology has described a novel mechanism by which the commensal pathogen Heliobacter hepaticus maintains its niche in the intestinal environment.
Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation
20 September 2017
Recent research from the Simon Group has discovered an unexpected novel role that autophagy plays during the generation of neutrophils.
3 April 2017
A new study published today in Nature Medicine could change the lives of millions of people living with inflammatory bowel diseases (IBD) who don’t respond to the current standard of care.
9 August 2016
Two Kennedy Institute scientists have proposed a solution to a puzzle of the human immune system: how our immune system scales its response in proportion to any threat to our health to make it 'just right'. Their ideas, published in the journal Trends in Immunology, could support a range of medical research.
23 July 2015
A new study led by researchers at the Kennedy Institute and published today in Immunity sheds light on the drivers behind Inflammatory bowel disease (IBD) and suggests potential new targets for treatment of the condition.
7 May 2015
Researchers at the Kennedy Institute, part of NDORMS have repurposed the approved drug miglustat to successfully slow the progression of multiple myeloma.
5 May 2015
By changing mouse genes to block a protein associated with obesity, researchers at the Kennedy Institute of Rheumatology, NDORMS have prevented fat from forming around the animals' internal organs, even when the animals eat an unhealthy diet. The study in Nature Medicine found that these genetically engineered mice also retained their sensitivity to insulin (normally blunted by obesity), despite gaining weight.