Nicholas Ilott
Postdoctoral Research Scientist
My interests lie in the interplay between the host and commensal microbes of the gut in the context of inflammation.
I am particularly interested in how host immune deficiencies (e.g IL10 signaling) in combination with microbial influences impact on disease development.
To explore these host-microbe relationships I am using a variety of high-throughput methods (microarrays, Next Generation Sequencing) in functional genomics and metagenomics analyses.
Recent publications
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Systems-level analysis of monocyte responses in inflammatory bowel disease identifies IL-10 and IL-1 cytokine networks that regulate IL-23
Internet publication
ASCHENBRENNER D. et al, (2019)
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Longitudinal metatranscriptomics reveals bacterial functions promoting gastrointestinal inflammation.
Working paper
JACKSON M. et al, (2019)
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Dysbiosis in the gut microbiome in cross-sectional studies of inflammatory arthritis patients.
Working paper
Thompson K. et al, (2019)
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Host-microbial crosstalk in the pathogenesis of inflammation and cancer in primary sclerosing cholangitis
Conference paper
Neyazi M. et al, (2019), JOURNAL OF CROHNS & COLITIS, 13, S20 - S21
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The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.
Journal article
Schulthess J. et al, (2019), Immunity, 50, 432 - 445.e7