Nicholas Ilott
Postdoctoral Research Scientist
My interests lie in the interplay between the host and commensal microbes of the gut in the context of inflammation.
I am particularly interested in how host immune deficiencies (e.g IL10 signaling) in combination with microbial influences impact on disease development.
To explore these host-microbe relationships I am using a variety of high-throughput methods (microarrays, Next Generation Sequencing) in functional genomics and metagenomics analyses.
Recent publications
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Host-microbial crosstalk in the pathogenesis of inflammation and cancer in primary sclerosing cholangitis
Conference paper
Neyazi M. et al, (2019), JOURNAL OF CROHNS & COLITIS, 13, S20 - S21
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The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.
Journal article
Schulthess J. et al, (2019), Immunity, 50, 432 - 445.e7
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Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.
Journal article
Ryzhakov G. et al, (2018), Nat Commun, 9
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Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I-driven CD8+ T cell response.
Journal article
Stockenhuber K. et al, (2018), J Exp Med, 215, 1987 - 1998
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A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-inflammatory Gene Signature in Macrophages.
Journal article
Danne C. et al, (2017), Cell Host Microbe, 22, 733 - 745.e5