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Publications

IL-1-driven stromal-neutrophil interaction in deep ulcers defines a pathotype of therapy non-responsive inflammatory bowel disease

Friedrich M. et al, (2021)

Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases

Korsunsky I. et al, (2021)

Gut microbiota: sculptors of the intestinal stem cell niche in health and inflammatory bowel disease.

Markandey M. et al, (2021), Gut Microbes, 13

Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease.

Ilott NE. et al, (2021), Wellcome Open Res, 6

Host-microbiota maladaptation in colorectal cancer.

Janney A. et al, (2020), Nature, 585, 509 - 517

Accurate identification and quantification of commensal microbiota bound by host immunoglobulins

Jackson MA. et al, (2020)

The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer.

McCuaig S. et al, (2020), Clin Cancer Res, 26, 4313 - 4325

IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation.

Corbin AL. et al, (2020), Sci Immunol, 5

Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies.

Ouahed J. et al, (2020), Inflamm Bowel Dis, 26, 820 - 842

Correction: Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling.

Ilott NE. et al, (2020), ISME J, 14

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2.

Mukhopadhyay S. et al, (2020), J Exp Med, 217

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.

Abeler-Dörner L. et al, (2020), Nat Immunol, 21, 86 - 100

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions.

Leng T. et al, (2019), Cell Rep, 28, 3077 - 3091.e5

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

Abeler-Dörner L. et al, (2019)

IgG-coating reveals maladapted interactions of a pre-colitic microbiome.

LAM L. et al, (2019)

Longitudinal metatranscriptomics reveals bacterial functions promoting gastrointestinal inflammation.

JACKSON M. et al, (2019)

Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease.

Friedrich M. et al, (2019), Immunity, 50, 992 - 1006

Regulatory T cell adaptation in the intestine and skin.

Whibley N. et al, (2019), Nat Immunol, 20, 386 - 396

Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation.

Miragaia RJ. et al, (2019), Immunity, 50, 493 - 504.e7

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.

Schulthess J. et al, (2019), Immunity, 50, 432 - 445.e7

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