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We have used a 0.35-kilobase (kb) antisense RNA probe complementary to the monomorphic regions of both classical and nonclassical HLA class I sequences to detect histocompatibility-class-I-antigen-specific mRNA in human testicular tissue. The message has been clearly detected in the interstitium while less intensive staining was revealed in the peribasal compartment of the seminiferous epithelium.

Type

Journal article

Journal

Exp Clin Immunogenet

Publication Date

1993

Volume

10

Pages

202 - 207

Keywords

Antisense Elements (Genetics), Gene Expression, Histocompatibility Antigens Class I, Humans, In Situ Hybridization, Male, RNA, Antisense, RNA, Messenger, Testis, Tissue Distribution