Bioinformatics

The OCMS supports the bioinformatics aspect of microbiome studies with our expertise in microbiome analysis and data interpretation. The centre has developed a number of computational pipelines that enable efficient and reproducible analyses of high-through put microbiome datasets. Our experience includes processing and analysis of 16S rRNA gene profiling and metagenomics analysis of various types of samples. Details on analysis methods and pipelines can be found on our github page and blog. 

As part of the Kennedy Institute of Rheumatology, the OCMS utilises a high-performance compute facility capable of storing and processing large datasets produced in microbiome studies. Part of the OCMS provision is access to this hardware and software via a dedicated bioinformatician capable of deriving important insights from complex datasets. 

The manner of bioinformatics support provided is flexible, based on individual projects’ needs, such as processing sequences to generate analysis-ready data or exploration of covariates and their associations with microbial profiles. We welcome consultation throughout your grant-writing process to advise on bioinformatic requirements on collaborative projects. Below is a general breakdown of the levels of bioinformatics support we provide, though the extent of bioinformatics support is always determined on a per-basis. 

Please contact us at ocms@kennedy.ox.ac.uk to enquire about our bioinformatics services.