Ekta Mukhopadhyay
DPhil
Postdoctoral Researcher in Mucosal Immunology
I am a Post- Doctoral Researcher in mucosal immunology working on pre-clinical evaluation of oral vaccines. I have been involved in vaccine research working on adenoviral (ChAd63 and ChAdOx1) and Virus-like particle vaccines (R21) for infectious diseases like malaria, HIV, influenza and zika. My past experience of working on process development, production and quality assessment of these vaccines made me curious about pre-clinical vaccine development which I was able to study during my DPhil in Clinical Medicine at the Jenner Institute. I have been a part of the Clinical Biomanufacturing Facility team and involved in process development and production of the first batch of the R21 vaccine for the Phase I clinical trial that has now advanced into Phase III trials.
During my DPhil, I have explored and assessed new malaria vaccine candidates for immunogenicity and efficacy that have provided promising results to progress into clinical trials. I have also investigated into alternative vaccination strategies and exploring glycans as malaria vaccine candidates. During this time, I got an opportunity to be a part of the Oxford/AZ ChAdOx1 nCov-19 coronavirus vaccine and R21 vaccine clinical trials.
Recent publications
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Journal article
Reinke S. et al, (2023), Cell Rep Med, 4
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Journal article
Mukhopadhyay E. et al, (2022), Biotechnol Bioeng
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Chapter
Mukhopadhyay E. et al, (2022), Vaccinology and Methods in Vaccine Research, 163 - 176
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Journal article
Ramasamy MN. et al, (2021), Lancet, 396, 1979 - 1993
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Journal article
Datoo MS. et al, (2021), Lancet, 397, 1809 - 1818
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Efficacy of a low dose candidate malaria vaccine, R21 in adjuvant Matrix-M™, with seasonal administration to children in Burkina Faso
Journal article
EWER K. et al, (2021), The Lancet
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Journal article
Voysey M. et al, (2021), Lancet, 397, 881 - 891
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Journal article
Barrett JR. et al, (2021), Nat Med, 27, 279 - 288
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Journal article
Voysey M. et al, (2021), Lancet, 397, 99 - 111
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Journal article
Kolli SK. et al, (2021), PLoS One, 16
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SAFETY, IMMUNOGENICITY AND DURABILITY OF A NOVEL MALARIA VACCINE CANDIDATE, R21 ADJUVANTED WITH AS01(B)
Conference paper
Venkatraman N. et al, (2017), AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 97, 132 - 132
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SAFETY AND IMMUNOGENICITY OF WITH NOVEL MALARIA VACCINE CANDIDATE, R21 ADJUVANTED WITH MATRIX M1
Other
Venkatraman N. et al, (2017), AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 95, 123 - 123