Clinical Trial Operational Lead – Experimental Medicine and Rheumatology
As Clinical Trial Operational Lead I am responsible for overseeing a growing portfolio of studies in experimental medicine and rheumatology (EMR) from inception to close out and archiving. I advise on and contribute to new research proposals, funding applications, and study protocols. Once studies are funded I oversee and support the work of the trial management team, providing advice on compliance with SOPs, relevant guidelines and regulations, with most studies running as part of the OCTRU portfolio.
I have over 14 years’ experience of working in clinical research. Prior to my current role I have managed a number of Investigator-led clinical trials in oncology and rheumatology. These include both CTIMPs and non-CTIMPs, covering phase 1 to 3, protocol development to analysis and close-out. I have also worked as a Clinical Trial Monitor and in trial administration.
My background and training is as a scientist, with a D.Phil in Plant Genetics from the University of Oxford and a BSc (Hons) in Biochemistry & Genetics (Cert Ind) from the University of Leeds.
If you are designing a new research study within experimental medicine and rheumatology please get in touch to benefit from the input of the experienced research team with EMR and OCTRU.
A successful strategy for recruiting participants not in a care
pathway to a CTIMP on time and to target
FRANCIS E. et al, (2019)
Anti-Tumour Necrosis Factor Therapy for Dupuytren's Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial.
Nanchahal J. et al, (2018), EBioMedicine, 33, 282 - 288
First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials.
Wasan HS. et al, (2017), Lancet Oncol, 18, 1159 - 1171
Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer.
Virdee PS. et al, (2017), JMIR Res Protoc, 6
SELECTIVE INTERNAL RADIOTHERAPY (SIRT) IN METASTATIC COLORECTAL CANCER PATIENTS WITH LIVER METASTASES: PRELIMINARY PRIMARY CARE RESOURCE USE AND UTILITY RESULTS FROM THE FOXFIRE RANDOMISED CONTROLLED TRIAL
Fusco R. et al, (2017), VALUE IN HEALTH, 20, A445 - A446