We are a world-leading basic and translational inflammatory sciences centre.
The three major themes of our research - immunity and microbiome, inflammation biology and tissue remodelling and repair - are relevant for a diverse range of chronic inflammatory disorders, including arthritis, inflammatory bowel disease, tissue fibrosis and certain types of cancer.
We apply state-of-the-art technologies in analysis of disease models and patient tissue samples to understand why disease develops and to reveal new diagnostic markers and targets for therapy.
Strategic partnerships with nearby clinical centres such as the Nuffield Orthopaedic Centre and the John Radcliffe Hospital facilitate scientific translation from bench to bedside.
OA CENTRE

LATEST NEWS
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Kennedy Institute launches Oxford Centre for Microbiome Studies
18 February 2019
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Professor Fiona Powrie set to take on cancer 'Grand Challenge'
23 January 2019
Select Publications
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Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?
Aungier SR. et al, (2019), Ann Rheum Dis, 78, 186 - 191
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CD45 exclusion– and cross-linking–based receptor signaling together broaden FcεRI reactivity
Felce JH. et al, (2018), Science Signaling, 11, eaat0756 - eaat0756
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Paracrine costimulation of IFN-γ signaling by integrins modulates CD8 T cell differentiation.
Krummel MF. et al, (2018), Proc Natl Acad Sci U S A, 115, 11585 - 11590
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Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.
Ryzhakov G. et al, (2018), Nat Commun, 9