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Publications

Pathogenic stromal cells as therapeutic targets in joint inflammation.

Dakin SG. et al, (2018), Nat Rev Rheumatol, 14, 714 - 726

TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions

Leng T. et al, (2018)

Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells.

Forbester JL. et al, (2018), Proc Natl Acad Sci U S A, 115, 10118 - 10123

Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.

Ryzhakov G. et al, (2018), Nat Commun, 9

Innate Lymphoid Cells: 10 Years On.

Vivier E. et al, (2018), Cell, 174, 1054 - 1066

Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I-driven CD8+ T cell response.

Stockenhuber K. et al, (2018), J Exp Med, 215, 1987 - 1998

Consequences of Identifying XIAP Deficiency in an Adult Patient With Inflammatory Bowel Disease.

Quaranta M. et al, (2018), Gastroenterology, 155, 231 - 234

Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease.

Uhlig HH. and Powrie F., (2018), Annu Rev Immunol, 36, 755 - 781

Helicobacter hepaticus polysaccharide induces an anti-inflammatory response in intestinal macrophages.

Danne C. and Powrie F., (2018), Microb Cell, 5, 208 - 211

NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.

Schwerd T. et al, (2018), Mucosal Immunol, 11, 562 - 574

CD161 Defines a Functionally Distinct Subset of Pro-Inflammatory Natural Killer Cells.

Kurioka A. et al, (2018), Front Immunol, 9

A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-inflammatory Gene Signature in Macrophages.

Danne C. et al, (2017), Cell Host Microbe, 22, 733 - 745.e5

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis.

Al-Mossawi MH. et al, (2017), Nat Commun, 8

Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation.

Hegazy AN. et al, (2017), Gastroenterology, 153, 1320 - 1337.e16

Th1 and Innate Lymphoid Cells Accumulate in Primary Sclerosing Cholangitis-associated Inflammatory Bowel Disease.

Gwela A. et al, (2017), J Crohns Colitis, 11, 1124 - 1134

Abstract SY19-03: Inflammation-driven cancer: Host and microbial pathways

Powrie F. et al, (2017), Cancer Research, 77

Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease.

Schwerd T. et al, (2017), Gut, 66, 1060 - 1073

Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8.

Fenton TM. et al, (2017), Mucosal Immunol, 10, 624 - 634

Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.

West NR. et al, (2017), Nat Med, 23, 579 - 589

Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells.

Chen HH. et al, (2017), J Allergy Clin Immunol, 139, 607 - 620.e15

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