Autophagy in the renewal, differentiation and homeostasis of immune cells.
Clarke AJ. and Simon AK., (2018), Nat Rev Immunol
Local exchange of metabolites shapes immunity.
Richter FC. et al, (2018), Immunology, 155, 309 - 319
B1a B cells require autophagy for metabolic homeostasis and self-renewal.
Clarke AJ. et al, (2018), J Exp Med, 215, 399 - 413
Autophagy dictates metabolism and differentiation of inflammatory immune cells.
Riffelmacher T. et al, (2018), Autophagy, 14, 199 - 206
In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Sanderson SL. and Simon AK., (2017), Aging Cell, 16, 1234 - 1243
Guidelines for the use of flow cytometry and cell sorting in immunological studies.
Cossarizza A. et al, (2017), Eur J Immunol, 47, 1584 - 1797
Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation.
Riffelmacher T. et al, (2017), Immunity, 47, 466 - 480.e5
Molecular definitions of autophagy and related processes.
Galluzzi L. et al, (2017), EMBO J, 36, 1811 - 1836
Mechanistic roles of autophagy in hematopoietic differentiation.
Riffelmacher T. and Simon A-K., (2017), FEBS J, 284, 1008 - 1020
Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.
Liao C. et al, (2017), Neurology, 88, 131 - 142
Exposure to zidovudine adversely affects mitochondrial turnover in primary T cells.
Wallace ZR. et al, (2016), Antiviral Res, 133, 178 - 182
Non-canonical autophagy LAPs lupus.
Simon AK. and Clarke AJ., (2016), Cell Death Differ, 23, 1267 - 1268
The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Kabat AM. et al, (2016), Elife, 5
The autophagy gene Atg16I1 differentially regulates T-reg and T(H)2 cells to control intestinal inflammation
Kabat AM. et al, (2016), ELIFE, 5
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ. et al, (2016), Autophagy, 12, 1 - 222
Evolution of the immune system in humans from infancy to old age.
Simon AK. et al, (2015), Proc Biol Sci, 282
Techniques for the Detection of Autophagy in Primary Mammalian Cells.
Puleston D. et al, (2015), Cold Spring Harb Protoc, 2015
Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.
Watson AS. et al, (2015), Cell Death Discov, 1
Mitochondrial DNA instability and dysregulated mitochondrial quality control contribute to progressive retinal ganglion cell loss in dominant optic atrophy
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