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Natural killer cells target antibody-bound cells following engagement of the Fc receptor CD16. Srpan et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201712085) reveal that activation-induced shedding of CD16 leads to more motile behavior, allowing more targets to be engaged and killed in a given time.

Original publication

DOI

10.1083/jcb.201807105

Type

Journal article

Journal

J Cell Biol

Publication Date

03/09/2018

Volume

217

Pages

2983 - 2985

Keywords

Killer Cells, Natural, Receptors, Fc, Synapses