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Researchers in the Centre for OA Pathogenesis Versus Arthritis at the Kennedy Institute of Rheumatology and Imperial College London are looking to recruit adults with painful hand osteoarthritis for an observational study to help uncover why people living with the condition experience different patterns of pain.

Elderly Person With Painful Hand © Shutterstock

Hand osteoarthritis is a common condition that affects more than 2 million people in the UK, affecting 1 in 4 people aged 50 years and over.

The Versus Arthritis-funded HOPE-c study is recruiting members aged 18 years old and over that live in the UK and have hand pain due to osteoarthritis. The study aims to answer the following questions: 

  • Are there different patterns of pain in hand osteoarthritis?
  • Can we identify factors that predict the future course of pain in hand osteoarthritis? 
  • Why do some people experience flares but not others? How does a flare impact a person’s life?

Participants will primarily be assessed remotely with optional face-to-face visits for participants who live near the main sites in Oxford and London (only when it is safe and feasible to do so, depending on local COVID-19 restrictions). A minimum of 5 assessments (electronic surveys) are carried over 26 weeks with up to three additional assessments if there are Flares/Changes in hand symptoms. These assessments include patient-reported questionnaires to assess pain, function, hormonal symptoms and mood with opportunities to submit hand photographs and x-rays. Participants will also be asked to score hand pain daily for six months, either using their mobile phone (using a secure weblink sent by daily SMS) or a paper diary. There is an optional follow-up for consenting patients at Year 2 and Year 5. 

The study is recruiting participants until September 2022. More information on taking part can be found on the HOPE-c website.