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Uzma Khan
Postdoctoral Researcher in Microbial Informatics
I’m Dr. Uzma Basit Khan, a computational biologist with a deep passion for understanding microbial genomics and metagenomics. Between February 2020 and June 2024, I had the privilege of working at the Sanger Institute as a Senior Computational Biologist on the JUNO project. My work focused on the evolution, epidemiology, and antimicrobial resistance of Group B Streptococcus (GBS) strains. During this time, I developed the first comprehensive GBS database and led the analysis of around 27,000 global GBS genomes, significantly enhancing our understanding of GBS disease and vaccine development.
Teaching and knowledge sharing are close to my heart. I’ve had the opportunity to serve as a bioinformatics trainer, conducting workshops across Colombia, Turkey, and Pakistan. In addition, I supervised various research projects and assisted JUNO partners with workflow analysis and manuscript preparation. My contributions to the field have even led to invitations as a plenary speaker at international conferences focused on GBS and pediatric infections.
I earned my PhD in Medicine from Cardiff University in 2020. My doctoral research centered on genomic and phenotypic profiling of antimicrobial resistance in GBS infections, emphasizing capsular switching, phylogenetic relationships, and the identification of lineage-specific genes as potential vaccine candidates.
Currently, I’m part of the NDORM team at the University of Oxford as a Postdoctorate, where I lead the analysis of metagenomes from IBD patients as part of the IBD Response project. My research aims to uncover associations between microbiome measures and responses to advanced treatments for IBD. Additionally, I’m establishing cutting-edge pipelines for metagenome assembly and annotation.
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