Contact information
Research groups
Colleges
Philippa Hulley
BSc Med, BSc Med (Hons), PhD
Associate Professor
- University Lecturer in Musculoskeletal Sciences
Associate Professor Hulley studied pattern formation during a developmental biology PhD at the University of Cape Town, South Africa, and followed this with post-doctoral work on cell signal transduction pathways in the Basel Preclinical Research Laboratories of Sandoz Pharma AG (now Novartis).
She joined the University of Stellenbosch, South Africa, as a Senior Scientist/Lecturer in 1996, and focused on mapping the changes in normal osteoblast signalling that are produced by clinical doses of glucocorticoids and which cause steroid osteoporosis.
Moving to Oxford, Assoc. Prof. Hulley was awarded a 5 year Arthritis Research UK Fellowship in 2004, University Research Lectureship in 2005, followed in 2007 by a 5 year RCUK Fellowship, teaching as Academic Fellow at St Hilda's College.
Since 2012, she has been University Lecturer in Musculoskeletal Sciences and a Tutorial Fellow at St Hilda's College.
Recent publications
-
Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution
Preprint
Mimpen JY. et al, (2024)
-
Single nucleus and spatial transcriptomic profiling of healthy human hamstring tendon.
Journal article
Mimpen JY. et al, (2024), FASEB J, 38
-
Use of oxygen-loaded nanobubbles to improve tissue oxygenation: Bone-relevant mechanisms of action and effects on osteoclast differentiation.
Journal article
Knowles HJ. et al, (2024), Biomaterials, 305
-
A roadmap for delivering a human musculoskeletal cell atlas.
Journal article
Baldwin M. et al, (2023), Nat Rev Rheumatol
-
Mature primary human osteocytes in mini organotypic cultures secrete FGF23 and PTH1-34-regulated sclerostin.
Journal article
Knowles HJ. et al, (2023), Front Endocrinol (Lausanne), 14
-
Single nucleus and spatial transcriptomic profiling of human healthy hamstring tendon
Preprint
Mimpen JY. et al, (2022)
-
A New Method to Sort Differentiating Osteoclasts into Defined Homogeneous Subgroups.
Journal article
Hulley PA. and Knowles HJ., (2022), Cells, 11
-
Platelet-rich plasma injection for acute Achilles tendon rupture : two-year follow-up of the PATH-2 randomized, placebo-controlled, superiority trial.
Journal article
Keene DJ. et al, (2022), Bone Joint J, 104-B, 1256 - 1265
-
Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study.
Journal article
Harrison P. et al, (2020), Platelets, 1 - 7
-
Synovial fluid fingerprinting in end-stage knee osteoarthritis: a novel biomarker concept.
Journal article
Jayadev C. et al, (2020), Bone Joint Res, 9, 623 - 632