Publications

Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis, increasing the risk of cerebrovascular complications

Dib L. et al, (2023), Nature Cardiovascular Research, 2, 656 - 672

Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites.

MacLean AJ. et al, (2022), Immunity, 55, 718 - 733.e8

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.

COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58

An immunodominant NP105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.

Peng Y. et al, (2022), Nat Immunol, 23, 50 - 61

Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates.

Simone D. et al, (2021), Commun Biol, 4

Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus

DOWNES D. et al, (2021), Nature Genetics

Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus.

Downes DJ. et al, (2021), Nat Genet, 53, 1606 - 1615

IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies.

Friedrich M. et al, (2021), Nat Med, 27, 1970 - 1981

RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus.

Jansen K. et al, (2021), Genome Res, 31, 2022 - 2034

Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury

Cross AR. et al, (2021)

Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance.

Aschenbrenner D. et al, (2021), Gut, 70, 1023 - 1036

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern DJ. et al, (2021)

SINGLE CELL ANALYSIS OF SPONDYLOARTHRITIS REGULATORY T CELLS IDENTIFIES DISTINCT SYNOVIAL GENE EXPRESSION PATTERNS AND CLONAL FATES

Simone D. et al, (2021), ANNALS OF THE RHEUMATIC DISEASES, 80, 17 - 18

IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors.

Swann JW. et al, (2020), J Exp Med, 217

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis.

Alivernini S. et al, (2020), Nat Med, 26, 1295 - 1306

Ciliary proteins specify the cell inflammatory response by tuning NFκB signalling, independently of primary cilia.

Mc Fie M. et al, (2020), J Cell Sci, 133

Cellular census of human fibrosis defines functionally distinct stromal cell types and states.

Layton TB. et al, (2020), Nat Commun, 11

IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation.

Corbin AL. et al, (2020), Sci Immunol, 5

GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis.

Regan-Komito D. et al, (2020), Nat Commun, 11

Rbfox contributes to a conservative program of self-antigen splicing in thymic epithelial cells

Jansen K. et al, (2020), bioRxiv

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Publications