A Langendorff-heart discovery pipeline demonstrates cardiomyocyte targeting by extracellular vesicles functionalized with beta-blockers using click-chemistry.
Park KC. et al, (2025), J Mol Cell Cardiol, 204, 89 - 100
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation.
Park KC. et al, (2023), Nat Cardiovasc Res, 2, 1221 - 1245
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy.
Subramaniam G. et al, (2023), Circ Res, 132, 828 - 848
Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.
Hulikova A. et al, (2022), Basic Res Cardiol, 117
Alkaline nucleoplasm facilitates contractile gene expressionin the mammalian heart
Hulikova A. et al, (2022), ACTA PHYSIOLOGICA, 236, 48 - 49
Elevated propionate signalling drives Pde9a overexpression and contractile dysfunction through increased histone acetylation and propionylation
Park KC. et al, (2022), CARDIOVASCULAR RESEARCH, 118
Elevated propionate/propionyl-CoA signalling drives Pde9a overexpression and contractile dysfunction through increased histone acetylation and propionylation
Park KC. et al, (2022), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 173, S50 - S50
Stored blood has compromised oxygen unloading kinetics that can be normalized with rejuvenation and predicted from corpuscular side-scatter.
Donovan K. et al, (2022), Haematologica, 107, 298 - 302
Off-target effects of sodium-glucose co-transporter 2 blockers: empagliflozin does not inhibit Na+/H+ exchanger-1 or lower [Na+]i in the heart.
Chung YJ. et al, (2021), Cardiovasc Res, 117, 2794 - 2806
SGLT2 inhibitors and the cardiac Na+/H+ exchanger-1: the plot thickens.
Chung YJ. et al, (2021), Cardiovasc Res, 117, 2702 - 2704
Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart.
Zervou S. et al, (2021), Front Physiol, 12
Single-cell oxygen saturation imaging shows that gas exchange by red blood cells is not impaired in COVID-19 patients.
Park KC. et al, (2020), Br J Haematol, 190, e229 - e232
Cardiac Complications of Propionic and Other Inherited Organic Acidemias.
Park KC. et al, (2020), Front Cardiovasc Med, 7
Off-target effects of SGLT2 blockers: empagliflozin does not inhibit Na/H exchanger-1 or lower intracellular Na in rat and mouse heart
Chung YJYJ. et al, (2020), EUROPEAN JOURNAL OF HEART FAILURE, 22, 283 - 283
Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity.
Chung YJ. et al, (2019), JCI Insight, 4
Evidence-based guidelines for controlling pH in mammalian live-cell culture systems.
Michl J. et al, (2019), Commun Biol, 2
Propionate anions produce acute and sustained remodelling of calcium transients in rat ventricular myocytes
PARK KC. et al, (2018), Journal of Inherited Metabolic Disease, 41, S37 - S219
Propionate anions accumulated in propionic acidaemia influences the cardiac gene expression landscape
Park KC. et al, (2018), Heart, 104, A4 - A5
Cardiac troponins: from myocardial infarction to chronic disease.
Park KC. et al, (2017), Cardiovasc Res, 113, 1708 - 1718