ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells.
Carretero-Iglesia L. et al, (2024), Nat Cancer
Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma.
Grandclément C. et al, (2024), Nat Commun, 15
Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma.
Pouleau B. et al, (2023), Blood, 142, 260 - 273
Metabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival.
Whitburn J. et al, (2022), Sci Adv, 8
EphA2 Is a Clinically Relevant Target for Breast Cancer Bone Metastatic Disease
Vaught DB. et al, (2021), JBMR Plus
Biodegradable Magnesium Alloys Promote Angio-Osteogenesis to Enhance Bone Repair
Han H-S. et al, (2020), ADVANCED SCIENCE
Modeling the Human Bone-Tumor Niche: Reducing and Replacing the Need for Animal Data.
Rao SR. et al, (2020), JBMR Plus, 4
Dysregulated Adiponectin Signalling via AdipoR1 Deletion Leads to Bone Loss and Increased Marrow Adiposity In Vivo Through Distinct Local and Systemic Mechanisms and in Contrast to Epidemiological Evidence
Sowman A. et al, (2019), JOURNAL OF BONE AND MINERAL RESEARCH, 34, 77 - 77
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease.
Gooding S. et al, (2019), Nat Commun, 10
Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment.
Olechnowicz SWZ. et al, (2019), Sci Rep, 9
Small Animal Video Tracking for Activity and Path Analysis Using a Novel Open-Source Multi-Platform Application (AnimApp).
Rao SR. et al, (2019), Sci Rep, 9
Current status and outlook on the clinical translation of biodegradable metals
Han H-S. et al, (2019), MATERIALS TODAY, 23, 57 - 71
Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300: response to correspondence by Borzì et al.
Sacitharan PK. et al, (2019), Exp Mol Med, 51, 1 - 2
A new corrosion-inhibiting strategy for biodegradable magnesium: reduced nicotinamide adenine dinucleotide (NADH).
Park J. et al, (2018), Sci Rep, 8
The polyphenol resveratrol promotes skeletal growth in mice through a sirtuin 1-bone morphogenic protein 2 longevity axis.
Zhao M. et al, (2018), Br J Pharmacol, 175, 4183 - 4192
Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300.
Sacitharan PK. et al, (2018), Exp Mol Med, 50
Corrosion behavior of biodegradable Mg-based alloys via femtosecond laser surface melting
Park J. et al, (2018), APPLIED SURFACE SCIENCE, 448, 424 - 434
Effect of spatial arrangement and structure of hierarchically patterned fibrous scaffolds generated by a femtosecond laser on cardiomyoblast behavior.
Jun I. et al, (2018), J Biomed Mater Res A, 106, 1732 - 1742
Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication.
Jun I. et al, (2018), Int J Mol Sci, 19