Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.
Zhu L. et al, (2022), Sci Transl Med, 14
TALAROZOLE, A RETINOIC ACID METABOLISM BLOCKING AGENT, SUPPRESSES MECHANOFLAMMATION AND ATTENUATES THE DEVELOPMENT OF POST-TRAUMATIC OA
Zhu L. et al, (2022), OSTEOARTHRITIS AND CARTILAGE, 30, S72 - S73
Murine joint destabilisation induces shear-responsive gene expression in the superficial cartilage which can be modified by a phospholipid-based lubricant
Zhu L. et al, (2021), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 102, A5 - A6
Thicker cartilage and chondroprotection after joint destabilisation in CTGF null mice is due to compensation by Activin A
Muhammad H. et al, (2021), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 102, A14 - A15
INTRA-ARTICULAR INJECTION OF PHOSPHOLIPID-BASED LUBRICANT REDUCES SHEAR-RESPONSIVE INFLAMMATORY GENES IN THE SUPERFICIAL LAYER OF CARTILAGE POST MURINE JOINT DESTABILISATION
Zhu L. et al, (2021), OSTEOARTHRITIS AND CARTILAGE, 29, S172 - S172
Molecular and skeletal characterization of mice with a fibrillin-1 mutation: insight into tissue bioavailability of TGF beta in Marfan syndrome
Wilson G. et al, (2021), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 102, 124 - 125
THE MICROBIOME DOES NOT INFLUENCE CARTILAGE DEGRADATION FOLLOWING JOINT DESTABILISATION IN MICE WHEN PERFORMED UNDER STRINGENTLY CONTROLLED CONDITIONS
Zarebska JM. et al, (2021), OSTEOARTHRITIS AND CARTILAGE, 29, S190 - S190
TNF alpha-stimulated gene 6 (TSG-6) is weakly chondroprotective in murine OA but does not account for FGF2-mediated joint protection
Zhu L. et al, (2021), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 102, 134 - 134
Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage.
Yang CY. et al, (2020), Osteoarthr Cartil Open, 2
Does pain at an earlier stage of chondropathy protect female mice from structural progression after surgically induced osteoarthritis?
von Loga IS. et al, (2020), Arthritis Rheumatol
IS THE PARADOXICAL INCREASE OF CARTILAGE THICKNESS IN CTGF NULL MICE DUE TO COMPENSATION BY ACTIVIN A
Muhammad H. et al, (2020), OSTEOARTHRITIS AND CARTILAGE, 28, S74 - S75
TNF ALPHA-STIMULATED GENE 6 (TSG6) IS CHONDROPROTECTIVE IN VIVO BUT OVEREXPRESSION CANNOT COMPENSATE FOR LOSS OF FGF2
Zhu L. et al, (2020), OSTEOARTHRITIS AND CARTILAGE, 28, S107 - S108
Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis.
von Loga IS. et al, (2019), Ann Rheum Dis, 78, 672 - 675
Connective tissue growth factor contributes to joint homeostasis and osteoarthritis severity by controlling the matrix sequestration and activation of latent TGFβ.
Tang X. et al, (2018), Ann Rheum Dis, 77, 1372 - 1380
CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy.
Miotla Zarebska J. et al, (2017), Osteoarthritis Cartilage, 25, 406 - 412
Brief Report: JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis.
Ismail HM. et al, (2016), Arthritis Rheumatol, 68, 1165 - 1171
VEGF release is associated with reduced oxygen tensions in experimental inflammatory arthritis.
Etherington PJ. et al, (2002), Clin Exp Rheumatol, 20, 799 - 805