Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance.
Clanchy FI. et al, (2024), J Autoimmun, 148
TNFR2 signalling in inflammatory diseases.
Williams RO. et al, (2024), Best Pract Res Clin Rheumatol
Bio‐marker detection redundancy improves sensitivity
Clanchy FIL., (2022), Clinical and Translational Discovery, 2
Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression.
Clanchy FIL. et al, (2022), J Autoimmun, 128
An integrated cytokine and kynurenine network as the basis of neuroimmune communication.
Stone TW. et al, (2022), Front Neurosci, 16
Induction of IDO1 and Kynurenine by Serine Proteases Subtilisin, Prostate Specific Antigen, CD26 and HtrA: A New Form of Immunosuppression?
Clanchy FIL. et al, (2022), Front Immunol, 13
Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS).
Ogbechi J. et al, (2022), Front Immunol, 13
Standardization of Antigen-Emulsion Preparations for the Induction of Autoimmune Disease Models.
Topping LM. et al, (2022), Front Immunol, 13
Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis
WILLIAMS R. et al, (2021), Proceedings of the National Academy of Sciences of USA
Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.
Huang Y-S. et al, (2021), Proc Natl Acad Sci U S A, 118
TLR expression profiles are a function of disease status in rheumatoid arthritis and experimental arthritis.
Clanchy FIL. et al, (2021), J Autoimmun, 118
Rationale for Early Detection of EWSR1 Translocation-Associated Sarcoma Biomarkers in Liquid Biopsy
Clanchy FIL., (2021), Cancers, 13, 824 - 824
TNFα inhibitors reduce bone loss in rheumatoid arthritis independent of clinical response by reducing osteoclast precursors and IL-20.
Al-Bogami M. et al, (2020), Rheumatology (Oxford)
Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al.
Aungier S. et al, (2020), Ann Rheum Dis, 79
IDO activation, inflammation and musculoskeletal disease.
Ogbechi J. et al, (2020), Exp Gerontol, 131
IDO and Kynurenine Metabolites in Peripheral and CNS Disorders.
Huang Y-S. et al, (2020), Front Immunol, 11
TNF receptor 2 signaling prevents DNA methylation at the Foxp3 promoter and prevents pathogenic conversion of regulatory T cells.
Tseng W-Y. et al, (2019), Proc Natl Acad Sci U S A, 116, 21666 - 21672
Ibudilast Inhibits Chemokine Expression in Rheumatoid Arthritis Synovial Fibroblasts and Exhibits Immunomodulatory Activity in Experimental Arthritis.
Clanchy FIL. and Williams RO., (2019), Arthritis Rheumatol, 71, 703 - 711
Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?
Aungier SR. et al, (2019), Ann Rheum Dis, 78, 186 - 191
Functional and phenotypic heterogeneity of Th17 cells in health and disease.
Bystrom J. et al, (2019), Eur J Clin Invest, 49