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PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling.

Journal article

McKee CM. et al, (2021), Biochem Soc Trans, 49, 2495 - 2507

Activation of a G protein-coupled receptor through indirect antibody-mediated tethering of ligands

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Cheloha RW. et al, (2021), RSC CHEMICAL BIOLOGY

TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.

Journal article

Fischer FA. et al, (2021), Proc Natl Acad Sci U S A, 118

Posttranslational and Therapeutic Control of Gasdermin-Mediated Pyroptosis and Inflammation.

Journal article

Fischer FA. et al, (2021), Front Immunol, 12

Improved GPCR ligands from nanobody tethering

Journal article

Cheloha RW. et al, (2020), Nature Communications, 11