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Inflammatory myofibroblastic tumours (IMTs) are an uncommon spindle cell neoplasm with a dense inflammatory infiltrate, usually encountered in children. IMTs of the central nervous system are extremely rare. This report describes the case of an IMT in a 61 year old man, in the pineal region. The tumour was completely excised, and immunohistochemistry demonstrated anaplastic lymphoma kinase 1 expression. There was no tumour recurrence during 18 months of follow-up. Our case extends both the age range and sites of occurrence of this rare tumour.

Original publication




Journal article


J Clin Pathol

Publication Date





981 - 983


Anaplastic Lymphoma Kinase, Brain Neoplasms, Humans, Male, Middle Aged, Neoplasms, Muscle Tissue, Pineal Gland, Protein-Tyrosine Kinases, Receptor Protein-Tyrosine Kinases