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Contact information


madelon.dejong@kennedy.ox.ac.uk


ORCID ID https://orcid.org/0000-0002-6145-6154


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Madelon de Jong

MD PhD

Arthritis UK Career Development Fellow

I am an Arthritis UK Career Development Fellow and clinician-scientist at the Kennedy Institute of Rheumatology, where I lead a research programme on bone marrow changes in autoimmune disease.

I trained in Medicine (MD) and Infection & Immunity (MSc) at Erasmus University Rotterdam, and completed my PhD at the Erasmus MC Cancer Institute (with Tom Cupedo and Pieter Sonneveld). During my PhD, I studied the bone marrow microenvironment in multiple myeloma, identifying inflammatory mesenchymal stromal cells (iMSC) with tumour-supportive and myeloid-modulatory properties (de Jong et al., Nature Immunology 2021), and I subsequently showed that stromal cells and neutrophils form a feed-forward inflammatory circuit in diseased bone marrow that persists despite therapy (de Jong et al., Nature Immunology 2024).

Building on this work, my current research focuses on how changes in blood cell production contribute to autoimmune disease, with the aim of identifying new therapeutic opportunities.

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