Lynn Williams

• Production of TNF-α in macrophages activated by T cells, compared with lipopolysaccharide, uses distinct IL-10-dependent regulatory mechanism.

  Agbanoma G. et al, (2012), J Immunol, 188, 1307 - 1317

• Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.

  Nicolaidou V. et al, (2012), PLoS One, 7

• Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes.

  Scott AJ. et al, (2011), J Biol Chem, 286, 35466 - 35476

• IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages.

  Smallie T. et al, (2010), J Exp Med, 207, 2081 - 2088

• Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures.

  Sacre SM. et al, (2008), J Immunol, 181, 8002 - 8009

• Role of STAT3 in glucocorticoid-induced expression of the human IL-10 gene.

  Unterberger C. et al, (2008), Mol Immunol, 45, 3230 - 3237

• Rac mediates TNF-induced cytokine production via modulation of NF-kappaB.

  Williams LM. et al, (2008), Mol Immunol, 45, 2446 - 2454

Recent Publications

• Production of TNF-α in macrophages activated by T cells, compared with lipopolysaccharide, uses distinct IL-10-dependent regulatory mechanism.

  Agbanoma G. et al, (2012), J Immunol, 188, 1307 - 1317
• Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.

  Nicolaidou V. et al, (2012), PLoS One, 7
• Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes.

  Scott AJ. et al, (2011), J Biol Chem, 286, 35466 - 35476
• IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages.

  Smallie T. et al, (2010), J Exp Med, 207, 2081 - 2088
• Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures.

  Sacre SM. et al, (2008), J Immunol, 181, 8002 - 8009