Contact information
Research groups
Jadwiga Zarebska
Senior Postdoctoral Scientist
POSTDOCTORAL RESEARCH ASSISTANT IN CARTILAGE BIOLOGY
I joined the Kennedy Institute in August 2013 in this newly created post when the OA Centre was established. Since 2013 my role has evolved as the Centre has grown. I am part of an interdisciplinary team of scientists and clinician researchers studying the pathogenesis of osteoarthritis. Central to this I provide training and supervision in specific techniques to other members of the group, as well as external researchers.
Recent publications
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Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.
Journal article
Zhu L. et al, (2022), Sci Transl Med, 14
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TALAROZOLE, A RETINOIC ACID METABOLISM BLOCKING AGENT, SUPPRESSES MECHANOFLAMMATION AND ATTENUATES THE DEVELOPMENT OF POST-TRAUMATIC OA
Conference paper
Zhu L. et al, (2022), OSTEOARTHRITIS AND CARTILAGE, 30, S72 - S73
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Murine joint destabilisation induces shear-responsive gene expression in the superficial cartilage which can be modified by a phospholipid-based lubricant
Conference paper
Zhu L. et al, (2021), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 102, A5 - A6
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Thicker cartilage and chondroprotection after joint destabilisation in CTGF null mice is due to compensation by Activin A
Conference paper
Muhammad H. et al, (2021), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 102, A14 - A15
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INTRA-ARTICULAR INJECTION OF PHOSPHOLIPID-BASED LUBRICANT REDUCES SHEAR-RESPONSIVE INFLAMMATORY GENES IN THE SUPERFICIAL LAYER OF CARTILAGE POST MURINE JOINT DESTABILISATION
Conference paper
Zhu L. et al, (2021), OSTEOARTHRITIS AND CARTILAGE, 29, S172 - S172