Claudia Monaco

• Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.

  Seneviratne AN. et al, (2017), Circulation

• Imaging vulnerable plaques by targeting inflammation in atherosclerosis using fluorescent-labeled dual-ligand microparticles of iron oxide and magnetic resonance imaging.

  Chan JMS. et al, (2017), J Vasc Surg

• Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

  Berbée JFP. et al, (2017), Atherosclerosis

• Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques.

  Langley SR. et al, (2017), J Clin Invest, 127, 1546 - 1560

• Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".

  Weber C. et al, (2016), Thromb Haemost, 116, 626 - 637

• Anti-TNF Therapy.

  Udalova I. et al, (2016), Microbiol Spectr, 4

• Multi-analyte profiling in human carotid atherosclerosis uncovers pro-inflammatory macrophage programming in plaques.

  Shalhoub J. et al, (2016), Thromb Haemost, 115, 1064 - 1072

• "Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques" (vol 89B, pg 168, 2015)

  Seneviratne AN. et al, (2016), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 91, 10 - 10

• Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques.

  Seneviratne AN. et al, (2015), J Mol Cell Cardiol, 89, 168 - 172

• Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development.

  Cole JE. et al, (2015), Proc Natl Acad Sci U S A, 112, 13033 - 13038

• Novel methodologies for biomarker discovery in atherosclerosis.

  Hoefer IE. et al, (2015), Eur Heart J, 36, 2635 - 2642

• B regulatory cells are increased in hypercholesterolaemic mice and protect from lesion development via IL-10.

  Strom AC. et al, (2015), Thromb Haemost, 114, 835 - 847

• Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4.

  Montecucco F. et al, (2015), Thromb Haemost, 114, 410 - 422

• Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.

  Ross EA. et al, (2015), J Immunol, 195, 265 - 276

• CROSSTALK BETWEEN CD248 AND PDGFR? REGULATES THE PATHOGENIC ROLE OF SMOOTH MUSCLE CELLS IN ATHEROSCLEROSIS

  Harrison M. et al, (2015), ATHEROSCLEROSIS, 241, E45 - E45

• ANTI-APOA-1 AUTOANTIBODIES INCREASE MOUSE ATHEROSCLROTIC PLAQUE VULNERABILITY, MYOCARDIAL NECROSIS AND MORTALITY TROUGH TLR2 AND TLR4-MEDIATED PATHWAYS

  Montecucco F. et al, (2015), ATHEROSCLEROSIS, 241, E27 - E27

• Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice.

  Terrando N. et al, (2015), Mol Med, 20, 667 - 675

• Role of inflammatory cells and toll-like receptors in atherosclerosis.

  Seneviratne AN. and Monaco C., (2015), Curr Vasc Pharmacol, 13, 146 - 160

• Macrophages and dendritic cells: the usual suspects in atherogenesis.

  Kassiteridi C. and Monaco C., (2015), Curr Drug Targets, 16, 373 - 382

• Interleukin-6 and microRNA profiles induced by oral bacteria in human atheroma derived and healthy smooth muscle cells.

  Pessi T. et al, (2015), Springerplus, 4

• Anti-TNF therapy: past, present and future.

  Monaco C. et al, (2015), Int Immunol, 27, 55 - 62

• PROTEOMICS ANALYSIS OF EXTRACELLULAR MATRIX IN MURINE ATHEROSCLEROSIS

  Skroblin P. et al, (2014), ATHEROSCLEROSIS, 237, E4 - E4

• Biomechanical factors in atherosclerosis: mechanisms and clinical implications.

  Kwak BR. et al, (2014), Eur Heart J, 35, 3013 - 3020d

• Cardiometabolic and immune factors associated with increased common carotid artery intima-media thickness and cardiovascular disease in patients with systemic lupus erythematosus.

  Ammirati E. et al, (2014), Nutr Metab Cardiovasc Dis, 24, 751 - 759

• Imaging of the vulnerable carotid plaque: biological targeting of inflammation in atherosclerosis using iron oxide particles and MRI.

  Chan JM. et al, (2014), Eur J Vasc Endovasc Surg, 47, 462 - 469

• Danger signals in cardiovascular disease.

  Frantz S. et al, (2014), Mediators Inflamm, 2014

• Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: influence of intraluminal flow.

  Caro CG. et al, (2013), J R Soc Interface, 10

• Toll-like receptors in atherosclerosis: a 'Pandora's box' of advances and controversies.

  Cole JE. et al, (2013), Trends Pharmacol Sci, 34, 629 - 636

• M1 macrophages are an early feature of shear stress modulated vulnerable atherosclerotic plaques

  Seneviratne AN. et al, (2013), EUROPEAN HEART JOURNAL, 34, 443 - 443

• Biomechanical factors and macrophages in plaque stability.

  Seneviratne A. et al, (2013), Cardiovasc Res, 99, 284 - 293

• Toll-like receptors in atherosclerosis.

  Falck-Hansen M. et al, (2013), Int J Mol Sci, 14, 14008 - 14023

• M1 MACROPHAGES AND IRF5 EXACERBATE ATHEROSCLEROTIC DISEASE

  Seneviratne A. et al, (2013), HEART, 99, A103 - A103

• Smooth muscle cells in human atherosclerosis: proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease.

  Viiri LE. et al, (2013), J Mol Cell Cardiol, 54, 65 - 72

• MACROPHAGE POLARISATION IN SHEAR STRESS MODULATED ATHEROSCLEROTIC PLAQUE VULNERABILITY

  Seneviratne AN. et al, (2012), ATHEROSCLEROSIS, 225, E2 - E2

• MACROPHAGE ACTIVATION DURING CHRONIC INFLAMMATION IN ATHEROSCLEROSIS

  Falck-Hansen MA. et al, (2012), ATHEROSCLEROSIS, 225, E3 - E3

• The role of Toll-like receptor-7 in arterial injury

  Sivagurunathan B. et al, (2012), JOURNAL OF HUMAN HYPERTENSION, 26, 621 - 622

• Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation.

  Salagianni M. et al, (2012), Circulation, 126, 952 - 962

• Antigen-dependent and antigen-independent pathways modulate CD4+CD28null T-cells during atherosclerosis.

  Ammirati E. et al, (2012), Circ Res, 111, e48 - e49

• Novel role of ADAMTS-5 protein in proteoglycan turnover and lipoprotein retention in atherosclerosis.

  Didangelos A. et al, (2012), J Biol Chem, 287, 19341 - 19345

• Host pattern recognition receptors (toll-like receptors, RIG-I-like receptors, NOD-like receptors) and atherosclerosis

  Feldmann M. and Monaco C., (2012), Inflammation and Atherosclerosis, 9783709103388, 353 - 383

• The metalloproteinase ADAMTS-5 is present in the vasculature and its expression is related to proteoglycan turnover and lipoprotein retention in atherosclerosis

  Didangelos A. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S78 - S78

• Proteomic study of atheroma-derived smooth muscle cells reveals signatures of increased oxidative stress and mitochondrial dysfunction

  Viiri LE. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S31 - S32

• Macrophage heterogeneity in shear stress modulated atherosclerotic plaque development

  Seneviratne AN. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S51 - S51

• Expression of the regulatory receptor CD200R on macrophages is regulated by polarization signals in atherosclerosis

  Falck-Hansen M. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S19 - S19

• B regulatory cells mediate atheroprotection via IL-10

  Cross A. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S118 - S119

• Arterial stent-associated intimal hyperplasia and wall hypoxia

  Caro CG. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S116 - S116

• Inflammation and underlying postoperative cognitive decline

  Terrando N. et al, (2012), BRITISH JOURNAL OF ANAESTHESIA, 108, 363P - 364P

• Toll-like receptors and macrophage activation in atherosclerosis.

  Seneviratne AN. et al, (2012), Clin Chim Acta, 413, 3 - 14

• The tolls and dangers of atherosclerotic disease.

  Monaco C., (2012), Curr Pharm Biotechnol, 13, 77 - 87

• Resolving postoperative neuroinflammation and cognitive decline.

  Terrando N. et al, (2011), Ann Neurol, 70, 986 - 995

• Late-phase contrast-enhanced ultrasound reflects biological features of instability in human carotid atherosclerosis.

  Shalhoub J. et al, (2011), Stroke, 42, 3634 - 3636

• Expression of the regulatory receptor CD200R on macrophages is regulated by polarization signals in atherosclerosis

  Falck-Hansen M. et al, (2011), IMMUNOLOGY, 135, 109 - 109

• A protective role for toll-like receptor 3 but not toll-like receptor 7 in intimal hyperplasia

  Cole J. et al, (2011), IMMUNOLOGY, 135, 106 - 106

• TOLL-LIKE RECEPTOR 3 EXPRESSION IS INCREASED IN ATHEROSCLEROSIS AND CONFERS PROTECTION AGAINST EARLY ATHEROSCLEROTIC LESION DEVELOPMENT AND WEIGHT GAIN IN APOLIPOPROTEIN E DEFICIENT MICE

  Cole JE. et al, (2011), HEART, 97, 1 - 1

• Targeting inflammation as a therapeutic strategy in accelerated atherosclerosis in rheumatoid arthritis.

  Full LE. and Monaco C., (2011), Cardiovasc Ther, 29, 231 - 242

• Comparative lipidomics profiling of human atherosclerotic plaques.

  Stegemann C. et al, (2011), Circ Cardiovasc Genet, 4, 232 - 242

• ANTI TNF THERAPY IN RHEUMATOID ARTHRITIS

  Feldmann M. et al, (2011), INFLAMMATION RESEARCH, 60, 31 - 31

• Innate immunity and monocyte-macrophage activation in atherosclerosis.

  Shalhoub J. et al, (2011), J Inflamm (Lond), 8

• Toll-like receptor signaling: common pathways that drive cardiovascular disease and rheumatoid arthritis.

  Monaco C. et al, (2011), Arthritis Care Res (Hoboken), 63, 500 - 511

• Multi-analyte profiling and pathway analysis reveals a predominance of pro-inflammatory M1-type macrophage polarisation and evidence of IL17/TH17 signalling in symptomatic human carotid atherosclerosis

  Shalhoub J. et al, (2011), BRITISH JOURNAL OF SURGERY, 98, 2 - 2

• Unexpected protective role for Toll-like receptor 3 in the arterial wall.

  Cole JE. et al, (2011), Proc Natl Acad Sci U S A, 108, 2372 - 2377

• Intra-plaque production of M1-type cytokines and matrix metalloproteinases differentiate stable from unstable carotid atherosclerosis

  Shalhoub J. et al, (2011), BRITISH JOURNAL OF SURGERY, 98, 3 - 3

• Innate immunity meets arteriogenesis: the versatility of toll-like receptors.

  Monaco C., (2011), J Mol Cell Cardiol, 50, 9 - 12

• Imaging of the vulnerable carotid plaque: biological targeting of inflammation using ultrasmall superparamagnetic particles of iron oxide (USPIO) and MRI

  Chan J. et al, (2011), BRITISH JOURNAL OF SURGERY, 98, 5 - 5

• Tumor necrosis factor-alpha (TNF) triggers a cytokine cascade yielding postoperative cognitive decline

  Terrando N. et al, (2010), IMMUNOLOGY, 131, 36 - 36

• Inhibitory effect of TIMP influences the morphology of varicose veins.

  Aravind B. et al, (2010), Eur J Vasc Endovasc Surg, 40, 754 - 765

• Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline.

  Terrando N. et al, (2010), Proc Natl Acad Sci U S A, 107, 20518 - 20522

• Treating atherosclerosis: the potential of Toll-like receptors as therapeutic targets.

  Cole JE. et al, (2010), Expert Rev Cardiovasc Ther, 8, 1619 - 1635

• Intra-plaque production of M1-type cytokines and matrix metalloproteinases differentiate stable from unstable carotid atherosclerosis

  Shalhoub J. et al, (2010), ATHEROSCLEROSIS, 213, E17 - E18

• Imaging of the vulnerable carotid plaque: Biological targeting of inflammation using ultrasmall superparamagnetic particles of iron oxide (USPIO) and MRI

  Chan J. et al, (2010), ATHEROSCLEROSIS, 213, E14 - E14

• Role of interleukin-1beta in postoperative cognitive dysfunction.

  Cibelli M. et al, (2010), Ann Neurol, 68, 360 - 368

• Proteomic analysis of smooth muscle cells derived from carotid plaque reveals differences between symptomatic & asymptomatic plaques

  Full L. et al, (2010), EUROPEAN HEART JOURNAL, 31, 319 - 319

• VISUALISING INFLAMED ATHEROSCLEROTIC PLAQUES: MOLECULAR IMAGING USING MRI AND TARGETED ULTRASMALL SUPERPARAMAGNETIC PARTICLES OF IRON OXIDE (USPIO)

  Chan J. et al, (2010), ATHEROSCLEROSIS SUPPLEMENTS, 11, 13 - 14

• The use of contrast enhanced ultrasound in carotid arterial disease.

  Shalhoub J. et al, (2010), Eur J Vasc Endovasc Surg, 39, 381 - 387

• The biology of carotid plaques: once unstable, always unstable?

  Sritharan K. et al, (2010), BRITISH JOURNAL OF SURGERY, 97, 1 - 1

• Tracking antigen-experienced effector T cells in vitro and in vivo.

  Gorman CL. et al, (2010), Methods Mol Biol, 616, 253 - 267

• The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction.

  Terrando N. et al, (2010), Crit Care, 14

• The expression and functions of toll-like receptors in atherosclerosis.

  Cole JE. et al, (2010), Mediators Inflamm, 2010

• Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis.

  Monaco C. et al, (2009), Circulation, 120, 2462 - 2469

• TOLL-LIKE RECEPTOR-2 MEDIATES INFLAMMATION AND MATRIX DEGRADATION IN HUMAN ATHEROSCLEROSIS

  Monaco C. et al, (2009), HEART, 95

• MRI OF ENDOTHELIAL ADHESION MOLECULES IN CAROTID ATHEROSCLEROSIS USING TARGETED ULTRASMALL SUPERPARAMAGNETIC PARTICLES OF IRON OXIDE

  Chan J. et al, (2009), HEART, 95

• Toll-like Receptor-2 and-4 Signaling Regulates Inflammation and Matrix Degradation in the Human Atherosclerotic Plaque

  Gregan SM. et al, (2009), CIRCULATION, 120, S1138 - S1138

• VISUALISING INFLAMED ENDOTHELIAL CELLS: MOLECULAR IMAGING USING MRI AND TARGETED USPIOS

  Chan J. et al, (2009), ATHEROSCLEROSIS SUPPLEMENTS, 10

• Proteomics of acute coronary syndromes.

  Didangelos A. et al, (2009), Curr Atheroscler Rep, 11, 188 - 195

• The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus.

  Full LE. et al, (2009), Arthritis Res Ther, 11

• Expansion of T-cell receptor zeta dim effector T cells in acute coronary syndromes.

  Ammirati E. et al, (2008), Arterioscler Thromb Vasc Biol, 28, 2305 - 2311

• C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes.

  Montecucco F. et al, (2008), J Leukoc Biol, 84, 1109 - 1119

• Additive prognostic value of interleukin-6 at peak phase of dobutamine stress echocardiography in patients with coronary artery disease. A 6-year follow-up study.

  Ikonomidis I. et al, (2008), Am Heart J, 156, 269 - 276

• Membrane type-1 matrix metal loproteinase is upregulated in symptomatic carotid atherosclerotic disease and along with other members of the quartenary complex regulated by pro-inflammatory cytolkines

  Sritharan K. et al, (2008), BRITISH JOURNAL OF SURGERY, 95, 934 - 934

• Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems.

  Lundberg AM. et al, (2007), Blood, 110, 3245 - 3252

• Cytokine and toll-like receptor dependent signalling in neointimal smooth muscle cells

  Finch JR. et al, (2007), ATHEROSCLEROSIS, 193, S3 - S3

• NF-kappa B inhibition by blockade of IKK-2 and MYD88 in vein graft smooth muscle cells reduces the expression of key mediators of intimal hyperplasia

  Finch J. et al, (2007), HEART, 93, A24 - A25

• TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues.

  Zhang Z. et al, (2007), Blood, 109, 4328 - 4335

• Tcrz(dim) lymphocytes define circulating effector cells that migrate to inflamed tissue

  Gorman CL. et al, (2007), RHEUMATOLOGY, 46, I44 - I44

• TCR-zeta dim T cells define a population of circulating effector cells that migrate to inflamed tissues

  Gorman CL. et al, (2007), ANNALS OF THE RHEUMATIC DISEASES, 66, A17 - A17

• Fluorescence lifetime imaging of unstained human atherosclerotic plaques

  Hegyi L. et al, (2007), HEART, 93

• TF ligation by factor VIIa induces pro-inflammatory cytokine production in atheroma smooth muscle cells

  Persson L. et al, (2006), EUROPEAN HEART JOURNAL, 27, 455 - 455

• Expansion of zeta-dim CD4+ T-cells and zeta-dim natural-killer (NK)-cells correlates with C-reactive protein (CRP) in patients with acute coronary syndromes (ACS)

  Ammirati E. et al, (2006), EUROPEAN HEART JOURNAL, 27, 971 - 971

• Cytokines for myocardial ischaemia: a echocardiographic study

  Raisakis K. et al, (2006), EUROPEAN HEART JOURNAL, 27, 561 - 561

• Inhibition of tissue factor signalling reduces production of pro-inflammatory cytokines in atheroma smooth muscle cells

  Persson L. et al, (2006), ATHEROSCLEROSIS SUPPLEMENTS, 7, 92 - 93

• Fluorescence lifetime imaging of unstained human atherosclerotic plaques

  Hegyi L. et al, (2006), ATHEROSCLEROSIS SUPPLEMENTS, 7, 587 - 587

• Enrichment of Z-dim CD4+ T-cells correlates with C-reactive protein (CRP) in patients with acute coronary syndrome (ACS)

  Ammirati E. et al, (2006), ATHEROSCLEROSIS SUPPLEMENTS, 7, 86 - 86

• T cells expressing low levels of TCRzeta preferentially migrate to sites of inflammation

  Gorman C. et al, (2006), ANNALS OF THE RHEUMATIC DISEASES, 65, A31 - A31

• T cells expressing low levels of TCR xi preferentially migrate to sites of inflammation

  Gorman CL. et al, (2006), RHEUMATOLOGY, 45, I17 - I18

• Down-regulation of zeta-chain in CD4(+)T-cells and in natural killer cells in patients with acute coronary syndrome (ACS)

  Ammirati E. et al, (2006), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 47, 328A - 328A

• What causes acute coronary syndromes? Applying Koch's postulates.

  Monaco C. et al, (2005), Atherosclerosis, 179, 1 - 15

• Persistent systemic inflammation in unstable angina is largely unrelated to the atherothrombotic burden.

  Monaco C. et al, (2005), J Am Coll Cardiol, 45, 238 - 243

• Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis.

  Monaco C. et al, (2004), Proc Natl Acad Sci U S A, 101, 5634 - 5639

• Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.

  Andreakos E. et al, (2004), Blood, 103, 2229 - 2237

• Protective role of low C-reactive protein levels against classical risk factors for coronary atherosclerotic disease

  Cianflone D. et al, (2004), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43, 293A - 293A

• Chlamydia pneumoniae heat shock protein 60 induces a highly specific persistent immune response in patients with unstable angina independently from IgG and IgA seropositivity

  Cianflone D. et al, (2004), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43, 489A - 489A

• T-cell-mediated signalling in immune, inflammatory and angiogenic processes: the cascade of events leading to inflammatory diseases.

  Monaco C. et al, (2004), Curr Drug Targets Inflamm Allergy, 3, 35 - 42

• Nuclear factor kappaB: a potential therapeutic target in atherosclerosis and thrombosis.

  Monaco C. and Paleolog E., (2004), Cardiovasc Res, 61, 671 - 682

• Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy.

  Andreakos E. et al, (2003), Arthritis Rheum, 48, 1901 - 1912

• REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN RHEUMATOID ARTHRITIS BY THE TRANSCRIPTION FACTOR NF kappa B

  Kiriakidis S. et al, (2003), RHEUMATOLOGY, 42, 42 - 43

• VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.

  Kiriakidis S. et al, (2003), J Cell Sci, 116, 665 - 674

• Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction.

  Andreakos E. et al, (2003), Blood, 101, 983 - 991

• Study of the myocardial contraction and relaxation velocities through doppler tissue imaging echocardiography. Anew alternative in the assessment of the segmental ventricular function

  Silva CES. et al, (2002), Arquivos Brasileiros de Cardiologia, 78, 206 - 211

• Direct analysis of gene expression and regulation in human atherosclerotic tissue: Nuclear factor kappa B regulates production of cytokines and tissue factor

  Monaco C. et al, (2002), CIRCULATION, 106, 259 - 259

• Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?

  Feldmann M. et al, (2002), Ann Rheum Dis, 61 Suppl 2, ii13 - ii18

• Inflammatory predictors of mortality in the Scandinavian Simvastatin Survival Study.

  Crea F. et al, (2002), Clin Cardiol, 25, 461 - 466

• Inhibition of VEGF in human macrophages and rheumatoid synovial cells by blockade of the NF kappa B pathway using adenoviral gene transfer

  Kiriakidis S. et al, (2002), JOURNAL OF MOLECULAR MEDICINE-JMM, 80, B3 - B3

• VEGF EXPRESSION IN HUMAN MACROPHAGES IS NF kappa B-DEPENDENT: STUDIES USING ADENOVIRUSES EXPRESSING A KINASE DEFECTIVE FORM OF IKK2 or I kappa B alpha THE NATURAL NF kappa B INHIBITOR

  Kiriakidis S. et al, (2002), RHEUMATOLOGY, 41, 66 - 66

• T cell-mediated signaling to vascular endothelium: induction of cytokines, chemokines, and tissue factor.

  Monaco C. et al, (2002), J Leukoc Biol, 71, 659 - 668

• SELECTIVE USAGE OF IKK2 FOR NF-kappa B ACTIVATION AND PRO-INFLAMMATORY GENE EXPRESSION: STUDIES IN HUMAN PRIMARY CELLS AND RHEUMATOID SYNOVIAL MEMBRANE CELL CULTURES

  Andreakos E. et al, (2002), RHEUMATOLOGY, 41, 65 - 65

• REQUIREMENT FOR NF kappa B AND IKK-2 IN TISSUE FACTOR EXPRESSION BY CELLS RELEVANT TO THE PATHOGENESIS OF ATHEROSCLEROSIS AND RHEUMATOID ARTHRITIS

  Monaco C. et al, (2002), RHEUMATOLOGY, 41, 32 - 32

• Risk of myocardial infarction and angina in patients with severe peripheral vascular disease: predictive role of C-reactive protein.

  Rossi E. et al, (2002), Circulation, 105, 800 - 803

• VEGF expression in human macrophages is NFkB-dependent: studies using adenoviral gene transfer

  Kiriakidis S. et al, (2002), EUROPEAN HEART JOURNAL, 23, 382 - 382

• NFkB and IkB kinase-2 regulate tissue factor and cytokine production in human atherosclerotic plaques: an analysis via adenoviral gene transfer

  Monaco C. et al, (2002), EUROPEAN HEART JOURNAL, 23, 261 - 261

• Inhibition of tissue factor by blockade of NFkB and IKK-2 using gene transfer: NFkB as a therapeutic target for reducing plaque thrombogenicity

  Monaco C. et al, (2002), EUROPEAN HEART JOURNAL, 23, 20 - 20

• Autoantibodies against oxidized low density lipoproteins in patients with stable angina, unstable angina or peripheral vascular disease; pathophysiological implications.

  Monaco C. et al, (2001), Eur Heart J, 22, 1572 - 1577

• [Cellular mechanisms of regulation of the inflammatory response in atherosclerosis: the role of cell contact-mediated signaling].

  Monaco C. et al, (2001), Ital Heart J Suppl, 2, 339 - 343

• Inhibition of tissue factor induction by blockade of the nuclear factor-kappa B pathway in human macrophages and endothelial cells using adenoviral gene transfer: Nuclear factor-kappa B as a potential therapeutic target for plaque stabilization

  Monaco C. et al, (2001), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 37, 289A - 289A

• Inflammatory predictors of mortality in the Scandinavian Simvastatin Survival Study

  Crea F. et al, (2000), CIRCULATION, 102, 699 - 699

• Activated T-cells stimulate endothelial cells to release proinflammatory cytokines in a contact-dependent manner: A clue about the pathogenesis of atherosclerosis?

  Monaco C. et al, (2000), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 35, 316A - 317A

• Chemokine production from endothelial cells is induced by activated T cells in a contact-dependent manner: a role for cell-cell contact interactions in the pathogenesis of atherosclerosis

  Monaco C. et al, (2000), EUROPEAN HEART JOURNAL, 21, 158 - 158

• Anti-oxidized LDL antibodies levels in patients with stable angina, unstable angina and peripheral vascular disease: pathophysiological implications

  Monaco C. et al, (2000), EUROPEAN HEART JOURNAL, 21, 655 - 655

• Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

  Monaco C., Atherosclerosis

Recent Publications

• Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.

  Seneviratne AN. et al, (2017), Circulation
• Imaging vulnerable plaques by targeting inflammation in atherosclerosis using fluorescent-labeled dual-ligand microparticles of iron oxide and magnetic resonance imaging.

  Chan JMS. et al, (2017), J Vasc Surg
• Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

  Berbée JFP. et al, (2017), Atherosclerosis
• Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques.

  Langley SR. et al, (2017), J Clin Invest, 127, 1546 - 1560
• Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".

  Weber C. et al, (2016), Thromb Haemost, 116, 626 - 637