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Antony Psarras
MD MSc PhD MRCP
NIHR Academic Clinical Lecturer in Rheumatology
- Academic Clinical Lecturer
- Honorary Specialty Registrar in Rheumatology, Nuffield Orthopaedic Centre
I am an Academic Clinical Lecturer and an Honorary Specialty Registrar in Rheumatology at the University of Oxford and the Nuffield Orthopaedic Centre. I qualified in Medicine from Aristotle University of Thessaloniki (Greece) in 2014 and I then followed postgraduate studies (MSc) in Immunology at Imperial College London. I successfully completed a PhD in 2018 investigating type I interferon regulation in the pathogenesis of systemic lupus erythematosus, supervised by Dr E. Vital and Prof P Emery at University of Leeds along with Prof G. Tsokos at Harvard Medical School.
After completing my Internal Medicine Training at King's College Hospital in London in 2022, I moved to Oxford to the Kennedy Institute of Rheumatology (NDORMS), supported by the NIHR Academic Clinical Lectureship scheme. My main clinical and research interest lies in systemic lupus erythematosus (SLE) and immune regulation of rheumatic diseases. I am currently focusing on immune cell metabolism and complex immunological networks in preclinical autoimmunity and established SLE. I am also affiliated to New College as Todd-Bird Junior Research Fellow in Clinical Medicine.
Key publications
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Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity.
Psarras A. et al, (2020), Nat Commun, 11
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Type I interferon–mediated autoimmune diseases: pathogenesis, diagnosis and targeted therapy
Psarras A. et al, (2017), Rheumatology, kew431 - kew431
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Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status
Md Yusof MY. et al, (2018), Annals of the Rheumatic Diseases, 77, 1432 - 1439
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Emerging concepts of type I interferons in SLE pathogenesis and therapy
Psarras A. et al, (2022), Nature Reviews Rheumatology
Recent publications
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Type 1 interferons: A target for Immune-mediated inflammatory diseases (IMIDs)
Mathian A. et al, (2025), Revue du Rhumatisme (Edition Francaise)
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Blood RNA-sequencing across the continuum of ANA-positive autoimmunity reveals insights into initiating immunopathology.
Carter LM. et al, (2024), Ann Rheum Dis
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Type 1 interferons: A target for immune-mediated inflammatory diseases (IMIDs).
Mathian A. et al, (2023), Joint Bone Spine, 91
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A cellular overview of immunometabolism in systemic lupus erythematosus
Psarras A. and Clarke A., (2023), Oxford Open Immunology, 4
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Management and treatment of children, young people and adults with systemic lupus erythematosus: British Society for Rheumatology guideline scope.
Md Yusof MY. et al, (2023), Rheumatol Adv Pract, 7
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Anti-BDCA2 Antibody for Cutaneous Lupus Erythematosus.
Psarras A. and Vital EM., (2022), N Engl J Med, 387, 1528 - 1529