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Luo Group | Statistical genomics and computational immunology
We develop statistical methods and computational software to better understand the genetic contribution to immune-mediated traits.
Johnson Group | Microbiome and Multi-omics
Kennedy
Applying multi-omic and computational genomic approaches to understand the molecular basis of host-microbiome interactions
Centre for OA Pathogenesis
Kennedy
Established in 2013, the Arthritis Research UK Centre of Excellence aims to develop new treatments for this disabling condition, improving healthcare and transforming people's lives.
Watt Group | Translational Research in Osteoarthritis
Our group tests findings from the laboratory in human clinical studies, and runs experimental medicine studies and clinical trials relevant to osteoarthritis within the Arthritis Research UK Centre for Osteoarthritis Pathogenesis.
Udalova Group | Genomics of Inflammation
Work in the Udalova is focused on understanding how the inflammatory response is controlled on the molecular level.
Buckley Group | Stromal Cell Biology
Kennedy
We aim to uncover the stromal basis of chronic inflammation and related tissue pathology to target fibroblasts across a range of immune-mediated inflammatory diseases.
Wann Group | Primary Cilia in Musculoskeletal Health and Disease
Cells use unique spaces to organise the messaging that modifies their behaviour and respond to their environment. Our research looks at how one such space - the primary cilium - affects the way cells respond to external cues including mechanical force and inflammatory cytokines.
Sansom Group | Computational and Single Cell Genomics Group
Work in the Sansom lab focuses on identifying the cellular and molecular causes of immune mediated inflammatory disease (IMID) using systems-level approaches.
Powrie Group | Mucosal Immunology
The Powrie lab employs basic and translational science to study host-microbe crosstalk in health and disease, focussing on inflammatory bowel disease (IBD), colorectal cancer (CRC) and inflammatory arthritis. Research spans observational and functional analysis of a broad range of cell types including bacteria, fibroblasts, T cells and neutrophils.
RIDD
The RIDD trial aims to test whether the progression of Dupuytren’s disease can be halted or slowed by treatment with anti-TNF injection. Currently, Dupuytren’s disease is left to progress until the finger deformity is severe enough to warrant a surgical procedure in hospital. If successful, anti-TNF treatment would prevent loss of hand function and the need for surgery, and would allow patients to be treated conveniently and quickly.
Midwood Group | Matrix Immunology
Our group investigates how the extracellular matrix - the component of tissue that lies immediately outside and between cells - contributes to inflammation.
Jostins Group | Statistical Genetics of Immune Variation
We seek to identify multi-gene signatures of shared immune variation to better understand disease genetics and health outcomes.