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International Women's Day
8 March 2021
It’s International Womens Day! This year’s theme is #Choosetochallenge. We’re celebrating some of the amazing women at NDORMS, and asking them what changes they’d like to see in medical sciences over the next 100 years.
Oxford to collaborate with Janssen to map the cellular landscape of immune mediated disorders
22 February 2021
The University of Oxford has entered into a strategic collaboration with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.
Versus Arthritis Foundation Fellowship awarded to Dr Kristina Zec
22 February 2021
Dr Kristina Zec has been awarded a Versus Arthritis Foundation Fellowship to investigate the role of products of lipid oxidation produced by synovial macrophages in triggering articular inflammation.
Vascular loss shown to be the primary hallmark of aging
4 February 2021
New Research from the Kusumbe group at the Kennedy Institute of Rheumatology identifies vascular attrition, marked by pericyte to fibroblast differentiation, as a primary hallmark of aging and highlights organ-specific vascular changes with age.
Immunology preprint reviews launched in Nature Reviews Immunology
15 January 2021
The Oxford-Mount Sinai (OxMS) Preprint Journal Club has partnered with Nature Reviews Immunology to launch a monthly Preprint Watch column.
Drug may boost vaccine responses in older adults
18 December 2020
A preliminary study shows that a drug which helps immune cells self-clean may improve vaccine protection in older adults
Living reviews launched by Oxford and Cardiff in the wake of COVID-19 research
18 December 2020
In a combined effort to help COVID-19 researchers the University of Oxford and Cardiff University have launched a series of “living reviews” in Oxford University Press’s new open access journal “Oxford Open Immunology”.
Oxford University awarded £2.4 million to fund DPhil research in inflammation, immunology and musculoskeletal disease
18 December 2020
Oxford University has today been awarded a £2.4 million grant, as part of the Kennedy Trust MB PhD scheme, to fund undergraduate medical students to undertake DPhil research in the areas of inflammation, immunology and musculoskeletal disease.
3D imaging reveals the role of blood vessels in hormone production
11 December 2020
New research from the Kusumbe Group at the Kennedy Institute has shown a direct correlation between age-related decline in capillary and artery numbers and hormone production in the endocrine system.
£3M invested to drive forward early translation through five new Oxford-Bristol Myers Squibb Fellowships
10 December 2020
Five new Oxford-Bristol Myers Squibb Fellowships representing an investment of £3M have been announced. The fellowships (formerly Oxford-Celgene) will support postdoctoral researchers and clinicians across five departments within the Medical Sciences Division and the Mathematical, Physical and Life Sciences Division, providing an opportunity for them to gain exposure to the field of commercial drug discovery and development.
New breakthrough in the treatment of rheumatoid arthritis
25 November 2020
People with Rheumatoid Arthritis (RA) could soon benefit from a new drug treatment that not only suppresses inflammation but also significantly reduces patient reported pain scores. Otilimab is a monoclonal antibody, biologic drug, which targets and suppresses the inflammatory cytokine GM-CSF.
Wellcome funding awarded to Oxford team to support research into heart muscle regeneration
24 November 2020
An Oxford team from the Centre for Medicines Development, Department of Physiology Anatomy and Genetics and Radcliffe Department of Medicine led by Professor Jagdeep Nanchahal at the Kennedy Institute has been awarded a Wellcome Innovator Award to develop a first in class therapeutic aimed at regenerating heart muscle after heart attack.
NDORMS researchers make Highly Cited Researchers list
19 November 2020
Professor Gary Collins, Professor Cyrus Cooper, Professor Fiona Powrie and the late Professor Doug Altman have been named on the annual Highly Cited Researchers™️ 2020 list from Clarivate.
Professor Katja Simon awarded Wellcome Trust Investigator Award
13 November 2020
Professor Simon has been successful in her Wellcome Trust Investigator Award entitled: “Proteostasis and Autophagy in Immune Senescence.”
NDORMS staff recognised for excellence in teaching and research
5 November 2020
Three NDORMS researchers have been awarded new titles in the University of Oxford's 2020 Recognition of Distinction exercise.
European Centre of Excellence at NDORMS
3 November 2020
NDORMS has been designated a EULAR Centre of Excellence 2020-2025, in recognition of our continued high-quality research publications in rheumatology.
An unexpected repair function for neutrophils
30 October 2020
In a collaboration with scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), Kennedy researchers have contributed to the discovery that neutrophils have many more functions in the body than previously thought. This finding suggests that neutrophil tissue-specific plasticity could be exploited in designing new treatments for neutrophil driven diseases, including cancer.
Understanding the physics of the immune response necessitates new technology
23 October 2020
Professor Marco Fritzsche has joined the Kennedy Institute as the Principal Investigator of the Biophysical Immunology Laboratory (BPI), as part of a joint appointment with the Rosalind Franklin Institute. His lab is leading the development of a lattice light sheet microscope that will significantly advance the study of live cells.
CD2 corolla calls T cells to arms
20 October 2020
A team from the University of Oxford has visualised how key cells of the immune system lock onto cancerous or infected cells to destroy them. The work was led by the Mike Dustin’s group at the Kennedy Institute of Rheumatology and experts in colorectal and ovarian cancers from across Oxford and computational biologists at the University of Birmingham.
Likely culprits causing blood vessel lesions in vasculitis identified
19 October 2020
NDORMS researchers identify a subset of immune cells that could be a new therapeutic target to treat inflamed blood vessels in Giant Cell Arteritis (GCA) and other forms of inflammatory vascular disease.