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Recent studies have identified interleukin 10 as a differentiation factor for a novel subset of immune suppressive regulatory T cells. Here, Hervé Groux and Fiona Powrie discuss the role that these cells play in the regulation of immune responses to enteric antigens and suggest that a deficiency in these cells might be involved in the pathogenesis of inflammatory bowel disease.


Journal article


Immunol Today

Publication Date





442 - 445


Animals, Cell Differentiation, Humans, Inflammatory Bowel Diseases, Interleukin-10, Mice, T-Lymphocyte Subsets