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We describe 2 patients with necrotizing vasculitis localized to the bowel, who were treated by excision of the involved tissue. Postoperatively, there was no evidence of active vasculitis, and both patients remain in remission on followup, without the use of immunosuppressive treatment. Evidence that an abnormal local microenvironment is necessary to sustain chronic inflammation may explain why surgical excision can be an important tool in the treatment of vasculitis.

Original publication

DOI

10.1002/1529-0131(199901)42:1<182::AID-ANR22>3.0.CO;2-4

Type

Journal article

Journal

Arthritis Rheum

Publication Date

01/1999

Volume

42

Pages

182 - 185

Keywords

Adult, Colon, Cyclophosphamide, Female, Humans, Male, Middle Aged, Postoperative Care, Vasculitis