Selective modulation of Natural Killer (NK) cell phenotypes through chromatin modifying mechanisms
Cribbs AP., Feldmann M., Soderstrom K., Oppermann U.
Natural killer (NK) cells are sentinels of the innate immune system by monitoring cell surfaces for the expression of MHC class I molecules and stress markers. For example, NK cells are critical for immune defence against malignant or virus infected target cells by engaging activating receptors, such as NKp30, leading to a cytolytic response.