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Cortical F-actin plays important roles during HIV-1 infection. A recent paper in Cell highlights the involvement of F-actin in enhancing dendritic cell (DC)-mediated HIV-1 infection of T cells. Such a critical mechanism of HIV-1 trans-enhancement between human DCs and T cells had not been analyzed in molecular detail before this work.

Original publication

DOI

10.1016/j.molmed.2016.03.007

Type

Report

Publication Date

05/2016

Volume

22

Pages

354 - 356