Membrane-type matrix metalloproteinase 4 (MT4-MMP) is a Met-zincin. It is a glycosylphosphatidylinositol (GPI)-anchored MMP. Unlike other MMP enzymes, MT4-MMP does not have strong proteolytic activity against extracellular matrix components, and its biological roles have not been clear until recently. In this chapter, various aspects of MT4-MMP so far reported, including Name and History, Activity and Specificity, Structural Chemistry, Preparation, Biological Aspects, are summarized.
10.1016/B978-0-443-28849-4.00110-7
Chapter
2025-01-01T00:00:00+00:00
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