Honorary Departmental Researcher
The human immune system can potently suppress tumour formation and progression, and cancer therapies designed to modulate anti-tumour immunity are now being vigorously investigated. However, it is also clear that neoplastic cells are capable of both evading and exploiting the immune system, such that cancer-induced immune activity can exacerbate disease. Chronic inflammation, for example, is associated with heightened cancer risk in multiple organ sites. It is therefore crucial that we develop a thorough understanding of both the beneficial and deleterious aspects of cancer immunity.
My major research interest is tumour immunology, (both its light and dark sides), and I am currently focused on characterizing novel cytokine pathways relevant to both inflammatory bowel disease and colon cancer.