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Lion Uhl

DPhil Student

I am a DPhil student in the group of Dr. Audrey Gerard investigating the role of T cell collectivity in the regulation of the CD8 T cell response.

I received my B.Sc. in Food Science and Biotechnology from the University of Natural Resources and Life Sciences, Vienna (BOKU) during which I conducted my bachelor's thesis under the supervision of Prof. Florian Rüker in the Christian Doppler Laboratory for Antibody Engineering. Because I equally enjoyed both the applied and more fundamental side of biomedical research I went on to complete two M.Sc. programs, one in Biotechnology (BOKU), specialising in Medical Biotechnology, and one in Molecular Biology (University of Vienna), specialising in Immunology. During my master's studies I got the opportunity to join as a Marshall Plan Fellow the group of Prof. Michel Nussenzweig at Rockefeller University, investigating first HIV-1 latency in patients on ART, before going on to focus on isolating and characterising anti-ZIKV neutralising antibodies from infected individuals in the wake of the Zika outbreak. Following my time in New York I returned to Vienna to finish my studies and to work for one year in the group of Dr. Christoph Bock at the Center for Molecular Medicine (CeMM) on various projects utilising high-throughput sequencing technologies to study cancer epigenomics before starting my DPhil at the Kennedy Institute of Rheumatology under the supervision of Dr. Audrey Gerard and Prof. Michael Dustin.

In our research we aim to better understand how different clones of CD8 T cells come together during priming to coordinate their response and co-regulate each other and their subsequent fate.

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