Krzywinski M., Bosdet I., Smailus D., Chiu R., Mathewson C., Wye N., Barber S., Brown-John M., Chan S., Chand S., Cloutier A., Girn N., Lee D., Masson A., Mayo M., Olson T., Pandoh P., Prabhu A-L., Schoenmakers E., Tsai M., Albertson D., Lam W., Choy C-O., Osoegawa K., Zhao S., de Jong PJ., Schein J., Jones S., Marra MA.

Using the human bacterial artificial chromosome (BAC) fingerprint-based physical map, genome sequence assembly and BAC end sequences, we have generated a fingerprint-validated set of 32 855 BAC clones spanning the human genome. The clone set provides coverage for at least 98% of the human fingerprint map, 99% of the current assembled sequence and has an effective resolving power of 79 kb. We have made the clone set publicly available, anticipating that it will generally facilitate FISH or array-CGH-based identification and characterization of chromosomal alterations relevant to disease.

set of BAC clones spanning the human genome.

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