Biologist, MSc Epidemiology, PhD
Epidemiologist of Translational Research in Osteoarthritis. My research is focused on osteoarthritis and joint surgery outcomes. I am interested in clinical, pharmaco-and device-epidemiology and social determinants on health. I am also interested to participate and lead research across different countries in international projects.
I joined the NDORMS department in June 2015. During this time I developed my skills generating predictive and survival models. I applied my expertise on clinical forecasting to patient reported outcomes in knee arthroplasty, fast progression to radiographic knee osteoarthritis, and biomarkers of cartilage regeneration and pain in injured knees. I used multiple imputation, bootstrapping, calibration and discrimination, and factor analysis to develop those studies. My research in the field of the pharmacoepidemiology looked at the impact of oral bisphosphonates in age-related macular degeneration and antirheumatic drugs on dementia. I used propensity score matching and survival modelling to conduct these studies. My ongoing work is centred on the assessment of an intervention to enhance the recovery pathway after primary hip and knee replacement surgery and the role played of hospital organisation and surgical factors on patient outcomes. I used interrupted time-series analysis among other statistical approaches to carry out this study.
My time at the NDORMS has allowed to me to disseminate 4 publications, 8 conference communications and 1 chapter of a report. I achieved an awarded grant as a co-applicant. I had a one-month secondment at the Geneva University Hospitals, Geneva, Switzerland.
I work with routinely collected extensive national databases that take patient activity, with practice of using data from the National Joint Registry (NJR), Hospital Episode Statistics (HES) database, NHS Patient Reported Measured Outcomes (PROMS), ONS mortality data, and Clinical Practice Research Datalink (CPRD).
My previous research has been focused on HIV. The main topic of my PhD was to determine how HIV-1 mutations contribute to antiretroviral resistance.
My experience includes data analysis, development of ad hoc software, data base design and implementation, and scientific dissemination trough conferences, medical and biochemical journals and official reports. Between 2000 and 2007 I worked in a research project involving a database generation and management of HIV sequences. In 2008 I joined the Carlos III Public Health Institute (Spain), gaining a wide experience in epidemiology of HIV and sexually transmitted infections. Between 2013 and 2014 I received additional training in a two-year field epidemiology programme (FETP).
Garriga C. et al, (2018), Ann N Y Acad Sci, 1415, 34 - 46
Garriga C. et al, (2020), Evid Based Ment Health
De Crescenzo F. et al, (2020), Evid Based Ment Health
Matharu GS. et al, (2020), J Arthroplasty, 35, 1521 - 1528.e5
OCCUPATION AND RISK OF KNEE OSTEOARTHRITIS AND KNEE REPLACEMENT: A LONGITUDINAL, MULTIPLE-COHORT STUDY
Perry TA. et al, (2020), OSTEOARTHRITIS AND CARTILAGE, 28, S415 - S416
PREDICTIVE FACTORS FOR PATIENT REPORTED SYMPTOMS AND RADIOGRAPHIC STRUCTURAL CHANGE AT 2 YEARS AFTER ACUTE KNEE INJURY
Garriga C. et al, (2020), OSTEOARTHRITIS AND CARTILAGE, 28, S322 - S323