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Anja Schwenzer

Postdoctoral Research Assistant

Citrullination is a post-translational modification of the amino acid arginine that occurs at sites of inflammation, and which is particularly elevated in chronic inflammatory diseases such as rheumatoid arthritis.

The aim of my work is to understand the impact of this modification on the extracellular matrix, especially how it affects the pro-inflammatory action of the matrix molecule tenascin-C.

I am also investigating whether citrullinated tenascin-C is targeted by the autoantibody response in rheumatoid arthritis. Together this information can help to improve both the diagnosis and treatment of arthritis.

Blue: citrulline
Green: unmodified arginines

Recent publications

Synovial matrix turnover controls immune cell spatial patterning in inflammation resolution.

Journal article

Richard J-B. et al, (2025), Mol Syst Biol, 21, 1638 - 1665

Investigating endogenous immune-mediated monocyte memory in rheumatoid arthritis.

Journal article

Marzeda AM. et al, (2025), Ann Rheum Dis, 84, 1484 - 1500

Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2.

Journal article

Gschwandtner M. et al, (2023), Int J Mol Sci, 24

More publications