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Centre for OA Pathogenesis
Established in 2013, the Arthritis Research UK Centre of Excellence aims to develop new treatments for this disabling condition, improving healthcare and transforming people's lives.
Kennedy Translational Innovation Group
We take an interdisciplinary approach from single-molecule imaging to multi-scale computational modelling and experimental validation to identify and develop therapeutic strategies for immune-mediated inflammatory disease.
Itoh Group | Cell Migration
We aim to understand the mechanisms behind uncontrolled cell migration - which promotes progression of certain conditions - to develop new treatments to prevent this progression.
Powrie Group | Mucosal Immunology
The Powrie lab employs basic and translational science to study host-microbe crosstalk in health and disease, focussing on inflammatory bowel disease (IBD), colorectal cancer (CRC) and inflammatory arthritis. Research spans observational and functional analysis of a broad range of cell types including bacteria, fibroblasts, T cells and neutrophils.
Sansom Group | Computational and Single Cell Genomics Group
Work in the Sansom lab focuses on identifying the cellular and molecular causes of immune mediated inflammatory disease (IMID) using systems-level approaches.
Fritzsche Group | Biophysical Immunology
Primary research goal is the identification and characterisation of the mechanisms of mechanobiology controlling the immune response in health and disease. Our objectives involve the application and development of novel ultrasensitive live-cell microscopy techniques with the right spatiotemporal sensitivity as demanded by the biology. Long-term goal of our research is the translation of our expertise and methodologies in mechanobiology to mechanomedicine in diagnostics and treatment of patients.
Udalova Group | Genomics of Inflammation
Work in the Udalova Lab is focused on understanding how the inflammatory response is controlled on the molecular level.
Gérard Group | Spatiotemporal Dynamics of T Cell Responses
We are interested in understanding how CD8 T cell responses are organised in space and time to achieve the correct balance between tolerance and immunity.
Hallou Group | Cell and Tissue Dynamics
Work in the Hallou Lab is focused on understanding how mechanical and biological signals control cell fate decisions and tissue dynamics in development, health and disease.
Arnon Group | Lymphocyte Trafficking and Adaptive Immunity
The main focus of the lab is to understand how humoral immune responses are regulated within the spleen.
Bezbradica Mirkovic Group | Innate Immune Sensing in Inflammation
We investigate how innate immune sensing pathways in macrophages control tissue inflammation.
Johnson Group | Microbiome and Multi-omics
Applying multi-omic and computational genomic approaches to understand the molecular basis of host-microbiome interactions