When immune cells detect harmful pathogens or cancer, they mobilise and coordinate a competent defence response. To do this effectively immune cells must communicate in a way that is tailored to the pathogenic insult. Consequently, the body's response to various health challenges depends on successful coordination among the cells of the immune system.
Oxford is the newest partner of the national Research into Inflammatory Arthritis Centre Versus Arthritis (RACE) which has been awarded continued funding of nearly \u00a32m over the next five years from Versus Arthritis.
The Kennedy Trust for Rheumatology Research (KTRR) has pledged a minimum of \u00a320M over five years to the Kennedy Institute of Rheumatology at the University of Oxford to support pioneering research into chronic inflammatory disease.
The Kennedy Institute recently hosted a visit from the National Rheumatoid Arthritis Society (NRAS) to explore opportunities to partner on patient involvement approaches in arthritis research.
Congratulations to Kennedy researchers Professor Chris Buckley, Professor Mark Coles and Dr Stephen Sansom who have been awarded \u00a31.5M funding from the Medical Research Council (MRC) to explore fibroblasts as an emerging target to treat chronic inflammatory disease.
Pioneering research by scientists at the Universities of Oxford and Birmingham published today in Nature brings us a step closer to developing targeted therapies for inflammatory diseases.
Dr Fiona Watt has been awarded a prestigious UK Research and Innovation (UKRI) Future Leaders Fellowship to further her research for better treatments for people living with, or at risk of the commonest form of arthritis, osteoarthritis.
Two articles from the Kennedy Institute review the latest in understanding immune control in the gut and skin and explain how this knowledge is being translated into new treatments for inflammatory disease
Oxford researchers gathered at the Kennedy Institute earlier this month to learn how advanced imaging technologies, such as super resolution microscopy, are pushing the boundaries of scientific discovery.
A recent workshop at Pembroke College, Oxford, provided a showcase for research within the Arthritis Therapy Acceleration Programme (A-TAP) aimed at speeding up the delivery of new drugs for immune-mediated inflammatory disease (IMIDs).
The Oxford Centre for Microbiome Studies (OCMS) provides unique access to essential technologies to speed up our understanding of how the microbes that inhabit our bodies influence health and disease.
Researchers in Oxford have found that an individual\u2019s immune system \u2013 and in particular the presence of T-cells amongst tumour cells \u2013 may play an important role in survival after surgery to remove pancreatic cancer.
Macrophages treated with the short-chain fatty acid butyrate \u2013 a by-product of dietary fibre breakdown - are better equipped to fight bacteria in the gut, report researchers from the Kennedy Institute and the Translational Gastroenterology Unit. These findings could lead to new strategies to restore gut health in inflammatory bowel disease (IBD).
Kennedy researchers, in collaboration with colleagues at the Botnar Research Centre, Oxford, and the Universities of Birmingham and Leeds, have been awarded strategic funding from the Medical Research Council (MRC) to map in detail the different types of cells that make up human joints.
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