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Professor Fiona Powrie recognised in Queen’s Birthday Honours

General

Professor Fiona Powrie was honoured in the 2022 Queen’s Birthday Honours List, published as Her Majesty celebrates her Platinum Jubilee.

The Kennedy Retreat

The whole of the Kennedy Institute decamped to St Catherine’s college in Oxford on 23/24 May to share and celebrate the Institute’s science, and to strengthen ties across individual research groups. It was great to have everyone back together face to face and the event was buzzing with excitement.

Breakthrough in treatment for Dupuytren’s disease

Department

Injection of the anti-TNF drug adalimumab into Dupuytren’s disease nodules is effective in reducing nodule hardness and nodule size.

Microbiome research at the Kennedy receives £2.8 million funding

The Kennedy Institute has been announced as one of 7 new research clusters by the MRC National Mouse Genetics Network

Wellcome Trust Investigator Award for Professor Arnon

Funding General

Congratulations to Professor Arnon on her successful Wellcome Trust Investigator Award entitled: “Spatiotemporal basis of adaptive immunity in the spleen.”

New research suggests targeting blood vessels could be key to controlling fibrotic disease

By studying blood vessels at single cell resolution, Professor Jagdeep Nanchahal and colleagues found that in Dupuytren’s disease, a fibrotic disorder of the hand, the vasculature is key to orchestrating the development of human fibrosis.

Defining the role of resident memory B cells in the fight against influenza

Researchers at the Kennedy Institute of Rheumatology have used 3D and live-imaging to show how resident memory B cells boost antibodies to fight influenza.

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

The COVID-19 Multi-omic Blood Atlas (COMBAT) has identified blood hallmarks of COVID-19 involving particular immune cell populations and their development, components of innate and adaptive immunity, and connectivity with the inflammatory response.

Oxford researchers awarded funding to study the immune response to malaria

Funding

Professors Matthew Higgins and Michael Dustin from the University of Oxford, Prof Gavin Wright from the University of York, and Professors Shiroh Iwanaga and Hisashi Arase from Osaka University have secured a Wellcome Collaborative Award for their study “How do RIFINs and STEVORs modulate human immunity during malaria?”

New funding awarded to study persistent pain in inflammatory arthritis

Funding

The £3.9M Wellcome Collaborative Award will be used to identify the drivers of pain in people living with rheumatoid arthritis.

Professor Chris Buckley joins the Kennedy Institute as Director of Clinical Research

Department

Moving to the University of Oxford with the Arthritis Therapy Acceleration Programme (A-TAP) will help accelerate the discovery of new treatments for inflammatory diseases.

Behind enemy lines: research finds a new ally in the fight against cardiovascular disease hidden within the vessel wall itself

A new study reveals the existence of a powerful ally in the fight against cardiovascular disease, a protective subset of vascular macrophages expressing the C-type lectin receptor CLEC4A2, a molecule which fosters "good" macrophage behaviour within the vessel wall.

New Oxford-Zeiss Centre of Excellence opens at the University of Oxford

Department General

The Kennedy Institute for Rheumatology and the Institute of Developmental and Regenerative Medicine announce the launch of the Oxford-Zeiss Centre of Excellence, providing state-of-the-art imaging technologies to lead future discoveries in global health and disease.

HOPE-c opens up for recruitment

Researchers in the Centre for OA Pathogenesis Versus Arthritis at the Kennedy Institute of Rheumatology and Imperial College London are looking to recruit adults with painful hand osteoarthritis for an observational study to help uncover why people living with the condition experience different patterns of pain.

Fiona Powrie honoured by British Society for Immunology

Awards

Fiona Powrie was one of four researchers from the University of Oxford recognised for their outstanding contributions to immunology with Honorary Lifetime Membership of the British Society for Immunology.

The Kennedy Institute scoops sustainability award

Awards Department

A new roof extension was awarded the 2021 Green Award for Sustainability by the Oxford Preservation Trust alongside a Certificate in the New Building category.

Fiona Powrie appointed new Deputy Chair of Wellcome’s Board of Governors

Department

Fiona Powrie, Director of the Kennedy Institute of Rheumatology at the University of Oxford has been selected as the next Deputy Chair of Wellcome’s Board of Governors.

A drug being trialled to treat cancer, could be the key to reducing gut inflammation

Publication

Published in Nature Communications, a new study reveals a new signalling pathway behind macrophage inflammatory activity

Single-cell ancestry vaccine research funded by the Chan Zuckerberg Initiative

Funding

The Chan Zuckerberg Initiative (CZI) has provided $2 million in funding to investigate how our ancestry and diversity influence the way that vaccines work in our cells.

Large genetic study suggests shared biological processes cause irritable bowel syndrome and anxiety

An international study of more than 50,000 people with irritable bowel syndrome (IBS) has revealed that IBS symptoms may be caused by the same biological processes as conditions such as anxiety. The research highlights the close relationship between brain and gut health and paves the way for development of new treatments.

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