Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Dr Sherlock joins the Kennedy Institute to lead a new research group examining the immunobiology of spondyloarthropathy

The Kennedy Institute would like to welcome Dr Jonathan Sherlock, who joins the Institute as a Senior Clinical Research Fellow funded by the Kennedy Trust for Rheumatology Research. Jonathan leads a new research group that will investigate the immunobiology of human spondyloarthropathy. 

Patients with ankylosing spondylitis or other spondyloarthropathies experience joint pain and stiffness. These symptoms are caused by inflammation and abnormal bone growth in the junctions where bones meet tendons called entheses.

Jonathan’s research will examine the molecular and cellular biology of spondyloarthropathy, with a focus on the role of inflammatory cytokines in driving disease. Current treatments for spondyloarthropathies target inflammation, but are not particularly effective at preventing abnormal bone growth. Jonathan’s studies will provide insight into disease pathogenesis, hopefully leading to better treatment options.

Jonathan will collaborate closely with Oxford Investigators Prof Paul Bowness, Prof Fiona Powrie and Prof Peter Taylor, as well as Prof Christopher Buckley (University of Birmingham).  Analysis of patient tissue samples will provide key component of these investigations.

Prior to joining the Kennedy Institute, Jonathan trained with Prof Christopher Buckley and Dr Daniel Cua (Merck Research Laboratories). His research identified a population of the immune cells in the enthesis that drive pathology in a disease model of spondyloarthropathy.

We wish Jonathan all the best in his new position.

Similar stories

Kennedy programmes support early career researchers

Since 2013 the Kennedy Institute of Rheumatology has been running a Career Development Programme, a scheme to help early career researchers launch their own independent laboratories, and more recently the Innovator Investigator Programme to bring new technologies to core research themes.

Kennedy researchers awarded funding to improve the understanding of inflammatory bowel diseases

A new £1.5M grant from the Medical Research Council (MRC) to the Powrie Group at the Kennedy Institute will help define different pathotypes of inflammatory bowel diseases that could lead to better and more focused treatments for patients.

Yoshi Itoh wins the International Dupuytren Award 2022

Yoshi Itoh, Associate Professor and Principal Investigator Cell Migration Group at the Kennedy Institute has been awarded the International Dupuytren Award 2022.

Professor Fiona Powrie recognised in Queen’s Birthday Honours

Professor Fiona Powrie was honoured in the 2022 Queen’s Birthday Honours List, published as Her Majesty celebrates her Platinum Jubilee.

Wellcome Trust Investigator Award for Professor Arnon

Congratulations to Professor Arnon on her successful Wellcome Trust Investigator Award entitled: “Spatiotemporal basis of adaptive immunity in the spleen.”

New Oxford-Zeiss Centre of Excellence opens at the University of Oxford

The Kennedy Institute for Rheumatology and the Institute of Developmental and Regenerative Medicine announce the launch of the Oxford-Zeiss Centre of Excellence, providing state-of-the-art imaging technologies to lead future discoveries in global health and disease.