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The ultra-thin super extended (UTSE) light sheet microscope enables researchers to follow up to 100,000 cells in space and in time, while maintaining single-cell resolution and a high control over the cells' microenvironment.


Contemporary gold-standard techniques used in immunology are limited by their low sensitivity and incapability to follow a large number of individual cells in space and in time. This results in a low statistical power, diminishing the sensitivity to small changes that may be biologically critical, and inability to capture rare events. We have developed a unique instrument which aims to overcome these limitations allowing both spatial and temporal imaging of 100,000 cells while maintaining single-cell resolution and a high control over the cells' microenvironment.
Ultra Thin Super Extended (UTSE) Light Sheet Microscope

MICROSCOPE OBJECTIVES:

  • Thorlabs TL4x-SAP 4x/0.20
  • Olympus Plan N 10x/0.25
  • Olympus Uplan SApo 20x/0.75
  • Olympus LMPlan FL N 50x/0.50

ILLUMINATION:

  • Toptica iChrome MLE-LFA-HP 405, 488, 561, 640 nm, <105 mW
  • Vortran 402, 442, 490, 512, 561, 639 nm

Software

 

Contact Veronika Pfannenstill.